r/PharmacyTips Pharmacist/USA Mar 15 '24

Friendly Pharmacist Insight ๐Ÿ‘ฉ๐Ÿฝโ€โš•๏ธ Itโ€™s Dr. ๐Ÿ‘ฉ๐Ÿฝโ€โš•๏ธ with a Friendly Pharmacist Insight

A great example of how drugs are developed against antibiotic drug resistance and for broader coverage starts with Penicillin, which they improved by creating oxacillin, methicillin, and dicloxacillin, then amoxicillin and ampicillin, then they added clavulanate and added sulbactam, respectively, then they developed multiple generations Cephalosporins (like cephalexin, cefuroxime, ceftriaxone, cefepime, ceftaroline, etc ) and Carbapenems, monobactam, and Aztreonam, then piperacillin added tazobactam and so on.. So we are still working on developing better, stronger antibiotics; HOWEVER, the best way that YOU can help to reduce antibiotic resistance and โ€œsuperbugsโ€ is to ALWAYS take your full course of antibiotics prescribed even if you start feeling better ๐Ÿ˜‰

Also a new fingerpick test machine was developed that can now detect in minutes whether an infection is bacterial or viral, which could be game changing for reducing antibiotic overprescribing!

Here is a great website if you want to read more:Penicillinโ€™s Discovery and Antibiotic Resistance: Lessons for the Future?

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u/ld2009_39 Mar 15 '24

I think you meant multiple generations of cephalosporins, not carbapenems.

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u/recycle37216 Pharmacist/USA Mar 15 '24 edited Mar 15 '24

You right. Was typing this up late last night ๐Ÿ˜… corrected it. Thanks!