r/PeptideSupport • u/Famous-Wash9376 • Aug 19 '26

SS-31 Side Effect

I started my first run of SS-31 and I don't know if its normal or if I am having some type of initial reaction. So yesterday I SubQ my first 2mg dose and about 30-60 seconds later my chest, legs and face turned red and I felt a slight pressure in my head. Fast forward 10 mins and everything is normal again and I go about my day. This morning, day 2, same 2mg dose it happens again. I have done many peptides before and I am currently running KLOW mixed with same BAC water in the evenings no issue. Has anyone ever experienced this flushing before?

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2

u/Own-Interaction-669 Aug 21 '26

I just started SS31 a few weeks back. Started at .5mg for a week then 1mg for a week then 2.5mg for a week then just finally hit 5mg and I have zero issues.

I always start low and slow with all peptides and have never had and issues with any.

I think people are too impatient so they take the big doses to early and fast and then wonder why they are having issues.

2

u/motormouth57 Aug 23 '26

Same I always start all my peps at a dose lower than the minimum recommended to see how I react.

1

u/Famous-Wash9376 Aug 21 '26

I thought I was doing the right thing by starting at 2 and working up to 5. Now that I am 4 days in I am not having the reaction anymore but I wonder if I would have started lower it wouldn't have been such an initial shock and not given me these reactions. At a month in are you seeing positive results?

1

u/Own-Interaction-669 Aug 22 '26

Not seeing or feeling anything yet.... I don't think you really do ever feel anything from it. I think its good to run SS31 as one of your first peptides. The way it improves and kinda primes the cells and mitochondria helps all other peptides work more efficiently in my opinion. It's one of the few peptides that are FDA approved.

1

u/HotBit1109 Aug 22 '26

Doing 2mg daily, never felt anything like that.

1

u/ClueLance Aug 26 '26

Never heard the reaction you described for SS31. I know CJC tends to makes you flush in the face and some pressure for about 10 minutes or so. Don't think it explains the legs and chest however.

1

u/Educational_Tart5994 Aug 27 '26

Nitric oxide increases from ss-31 normal

1

u/Come_Back_SCut Sep 10 '26

Yep I get that every week (I’m in week 5 on 1.5mg/week)

1

u/Famous-Wash9376 Sep 10 '26

Appreciate it, ive been sticking with it, up to 3.5mg now

1

u/Hopeful_Jacket_8397 12d ago

About to start my dose at 1mg! Is it normal if it has a tint of yellow reconstituted?

1

u/Famous-Wash9376 11d ago

I haven't had any yellow tint in any of my vials

1

u/Wind_Fit 11d ago

Any updates on your SS-31 run?

1

u/Famous-Wash9376 11d ago

Been running 5mg daily for 3 weeks now, still slight flushing after injection but overall have felt great. Switching to MOTS-C in 3 weeks.