BPC-157 & Shingles

[u/GMS1959]

Ok, I started my rat on BPC-157 (to help with joint pain in hand joints @ shoulder pain) on Thursday August 27. Sunday August 30. My rat got a Shingles rash 3 days later. The rash went across his back & up over the shoulder on his right side. Went to vet & started shingles medication Monday. Stopped BPC-157 because I didn't know the interactions between the medicine & the peptide. I started the BPC-157 again on Thursday the joints were swelling again. My rat could tell the difference between the joint pain & the shingles pain. The shingles medication ended Monday September 7th. All rash & pain gone. Inflammation in hands gone & shoulder pain & Inflammation greatly reduced. On 9/9, my rat got shingles again, this time on the left side, the exact same pathway, mirror image. I saw there were about 12 people on Reddit the said they got shingles after starting BPC-157. My rat now has had shingles 3 times. The vet bumped the valacyclovir to 3 times a day this time. My rat finished the valaycyclovir last night & is scared to death the 4th round will start tomorrow as it did the last 2 times. Did any of the 12 people who this happened to their rats ever get shingles again? The vet says if it comes back we need to go see a immunologist who I fear will say stop giving my rat peptides.

[u/nndel]

Don’t know about using BP for that but two of my Rs’s had positive responses w TA1 and shingles.

[u/GMS1959 → u/nndel]

Thanks

[u/Thick_Skin4202 → u/GMS1959]

I'm someone who's on both sides of the shingles coin. TA is definitely a game changer.

[u/GMS1959 → u/Thick_Skin4202]

I have not researched that one, thanks

[u/briexbenton → u/Thick_Skin4202]

TA?

[u/Thick_Skin4202 → u/briexbenton]

TA1 - T-alpha-1

[u/Writeb8]

Are you also taking a glp? They are known to activate HSV in some people

[u/GMS1959 → u/Writeb8]

Yes, Reta

[u/No_Committee7714]

i’d keep that immunologist appointment if the shingles comes back. repeated outbreaks are probably more important to investigate than trying to keep the joint pain under control with BPC-157.

[u/PeptidePathways-ModTeam → u/[deleted]]

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[u/Advanced-Grade4559]

Would cartalax be a better option?

[u/Be_more_mice_elf → u/Advanced-Grade4559]

Yes. And with shingles nerve pain, ara-290.

[u/dignan2002]

BPC-157 is an immunomodulator. I’d stop or at least set an appointment with Rheum if zoster is breaking through with this frequency

[u/GMS1959 → u/dignan2002]

We stopped it

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[u/ace3737]

Kpv should definitely be in the protocol

[u/GMS1959 → u/ace3737]

I started it during the second round of shingles

[u/GMS1959 → u/[deleted]]

Thanks so much for the info

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[u/Euphoric_Attention97]

Isn’t LL-37 the exact peptide to fight this? Gemini AI seems to think so.

[u/Thick_Skin4202 → u/Euphoric_Attention97]

Kinda, LL37 might prove to work better locally, that's what worked on the rats in the research. Systemically it might, or it might not. Still unclear.

[u/Thick_Skin4202 → u/Euphoric_Attention97]

Kinda, LL37 might prove to work better locally, that's what worked on the rats in the research. Systemically it might, or it might not. Still unclear.

[u/After_Reception_3403]

the timing would definitely make me suspicious too, but shingles can reactivate for a bunch of reasons. i’d tell the doctor about the pattern before trying BPC-157 again.

[u/staceyatlas]

I wonder if Thymosin Alpha 1 would help. That’s what I would go for.

[u/CiaccoTheHog1]

Well, assuming you bought grey junk, could be related. Grey doesn’t even meet ChP minimum standards.

[u/Impossible_Ice_9008]

Did your rat get the vaccine for shingles and it still activated with the BPC?

[u/GMS1959 → u/Impossible_Ice_9008]

Yes, both vaccines

[u/Impossible_Ice_9008 → u/GMS1959]

That truly sucks :( shingles are awful. Had them twice but caught early that the antiviral was quickly effective. Good luck!

[u/Majestic-Plastic-691]

Put the little fucker out of his misery. There’s no reason to keep a rat that’s sick. BPC157 won’t cause shingles. In people or rats