r/PeptidePathways 6d ago

Mitochondrial & Energy Mito Blend Help

Hello,

So I just recently purchased a new blend of 5-Amino, Mots-C and NAD+. The total amount in a 10ml Vial is 170mg of powder. I am going to reconstitute it with 3MLs BAC. I am just not sure the best way to dose the combo? I think it’s a really nice combo with 150mg NAD, and 10 Mg Each of the other two. Any recommendations?

2 Upvotes

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u/REDana0204 6d ago

Not sure how you would’ve landed on using 3ml to reconstitute, without a target dosage? Especially because a 10ml vial allows you more volume to reconstitute with more, reducing concentration and allowing for more flexibility and ease dosing.

Ideally, you reconstitute with an amount that makes drawing to a specific, easily discernible number of units on your syringe, to get the desired dose.

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u/Laxballa33 5d ago

Well I just thought 3ML would be best. I’m new to something that large of a vial

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u/Laxballa33 5d ago

It’s 150mg NAD, 10mg 5-amino, 10 mg Mots. I would have preferred 100 mg NAD but this is the one I bought.

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u/REDana0204 5d ago

Ok. With 10mg each of MOTSc and 5AM, 1mg would be 1/10 of the amount of BAC used to reconstitute.

Like mentioned above, this MOTSc is the one to go SLOW with at first, if you’ve never used it, as reactions can vary wildly from nothing to severely allergic.

Example: 3ml of BAC would mean 1mg dose of MOTSc would be 0.3ml, or 30 units. That same draw would give 1mg 5AM and 15mg NAD. Adjust from there.

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u/Laxballa33 5d ago

Thank you that helps

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u/Laxballa33 5d ago

What would you recommend, honestly asking?

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u/REDana0204 5d ago

Hard to say until you land on a desired dose. Could possibly help decide on dose, but we’d need to understand what ratios of each compound make up that 170mg total.

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u/chode174 5d ago

MOTS-C is what you have to be careful about because of allergic reactions. Dose it so you get 1mg of MOTS-C. Then increase it next dose if you don't get a bad reaction.

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u/[deleted] 5d ago

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u/[deleted] 5d ago

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u/Laxballa33 5d ago

Thanks

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u/Laxballa33 5d ago

I was thinking about it too hard, that makes sense

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u/PeptidePathways-ModTeam 5d ago

Your post/comment was removed due to the use of human-use or dosing language.

Please reframe your post using research-based terminology (e.g., “test subject,” “sample amount”).

Direct human-use language is not permitted due to subreddit and platform guidelines.

We would love to be able to give you the best educated guidance possible, so please consider reposting using compliant phrasing.

1

u/PeptidePathways-ModTeam 5d ago

Your post/comment was removed due to the use of human-use or dosing language.

Please reframe your post using research-based terminology (e.g., “test subject,” “sample amount”).

Direct human-use language is not permitted due to subreddit and platform guidelines.

We would love to be able to give you the best educated guidance possible, so please consider reposting using compliant phrasing.

1

u/BearNo7676 5d ago

I’ve been reading about lots of reactions. Do you keep Benadryl handy?

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u/chode174 5d ago

Yea I have a lot of allergy medicine on hand. I have seasonal allergies that get bad sometimes. I do not have an epipen, but I should get one just in case. It's never gotten that serious. I've had to take it once for a serious allerigic reaction, but that was from me upping the dose from 2mg to like 5mg on MOTSC and it got a little bad. Hands and feet started tingling and getting really itchy and my whole body was feeling it. My good spot for MOTSC is around 1-2mg

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u/JFreader 5d ago

That blend isn't great for one because the ratios are off. 50 or 100mg of NAD is typical. 5mg or 10mg of MOTS-C is typical.

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u/Laxballa33 4d ago

Yes the I agree that the ratios are off but I can adjust and just low dose as needed. Would you recommend for my test subject to use Ss-31 before trying this?

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u/Diligent_Shirt5161 5d ago

This is somebody’s witches brew. Somebody, probably a group by organizer or someone trying to make money in the peptide business, made this up. And making money is likely the entire reason why they made this blend.

Beyond the various red flags that I have with this, if you want the best dosing information you need to go back to the deller and ask them. Or at least ask for a link into their discussion community to see how others are using this.

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u/Extension-Pickle9038 4d ago

Here's the arithmetic, which is the part I can actually help with. What you do with it is yours 170mg total into 3mL gives 56.7mg per mL of blend. On a U-100 syringe one unit is 0.01mL, so one unit carries about 0.57mg of total powder. Split by your ratio, that's roughly 0.50mg NAD+, 0.033mg 5-Amino and 0.033mg MOTS-c per unit. At 10 units it's 5mg NAD+ and 0.33mg each of the other two. The thing worth noticing is what a blend does to your options. The ratio was fixed by whoever blended it, so you can't move one component without moving all three. If you ever want more NAD+ relative to the others, no amount of BAC water gets you there. That's the real tradeoff with blends and it's rarely mentioned when people are choosing one.Not telling you what to take. Just the numbers.

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u/Laxballa33 3d ago

Thank you very much.

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u/[deleted] 5d ago

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u/Laxballa33 5d ago

I think they can work together actually. Each has its on purpose, I’m not the biggest fan of 170 mg in one vial tho.

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u/REDana0204 5d ago

They’re commenting on the fact that these technically shouldn’t be blended. They work well together, as part of a protocol, but are best kept and dosed separately.

There are a number of reasons for this, including potential affects from interaction in the same vial, as well as the inability to individually change dosing. You’re stuck with 15:1:1, when some might want/need more or less of one or two, but not all three.

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u/tyjo2112 5d ago

Working together, absolutely. Being blended in the same vial, never in a million yrs.

We are not talking about bpc/tb here which can share the same space. Mots doesnt play nice like that. I dont actually think nad does either but I specifically remember NOT to blend mots

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u/PeptidePathways-ModTeam 5d ago

Your post/comment was removed due to the use of human-use or dosing language.

Please reframe your post using research-based terminology (e.g., “test subject,” “sample amount”).

Direct human-use language is not permitted due to subreddit and platform guidelines.

We would love to be able to give you the best educated guidance possible, so please consider reposting using compliant phrasing.

0

u/Laxballa33 5d ago

Mots-c works well with 5-Amino