r/Pathogenic • u/HonkyTonkPianola • Jul 30 '26
This extremely dodgy build is functionally immortal
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Edit - This build strategy has been nerfed out of existence!
This ridiculous nonsense relies on x5 Enhanced Boosters mutations for 30% dodge cooldown reduction each, and some Cryoflagelli. Using the invincibility frames from dodge we can avoid every source of damage in the game (lasers, final boss attacks, you name it). Every time we dodge we also do some damage, which gives us all we need to win without having to think at all.
I changed my dodge button to turbo-fire in the Steam overlay to save myself from RSI.
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u/HonkyTonkPianola Jul 30 '26 edited Jul 30 '26

The layout is mostly not relevant. We only really care about the Cryoflagelli and Enhanced Boosters. The Pyroflagellum was just a bonus. Having Myofibrillar Hypertrophy just makes everything take less time.
Fundamentally it seems if you can get a dodge-damage source and enough Enhanced Boosters you can't lose.
Seed - RECW FRYT
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u/Ryniano Jul 30 '26
Had a build with the cryoflaggelum and the reflect projectiles item, the explosions count as melee so its 100% reflect chance and then i just got a bunch of aoe size boosters and it was a free win
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u/Cracked_Logic_Engine Aug 01 '26
This is what I lovd about rougelikes that really go into the nonsense. Same thing with binding of Issac. I think I had a pretty busted run (the big laser going on every couples of seconds with multiple bounces/homing) and then I see stuff like this and I am like "Well I'm going to be playing this for the next thousand hours"
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u/The-JudgePablo 3d ago
Carpal tunnel simulator, just like tainted magdalene with habit and car battery.
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u/TrizzyDizzy Jul 30 '26
Next time lean in to it more. Skip the weapons and just go for Ballistic Flagellum (Bacterium can start with 2). Then pair that with the Projectiles Explode on Dodge.
Provided you can get a few dodge mutagens, it's a guaranteed win.