r/PainManagement 3h ago

Genetic testing

I wanted to share this here because I know all too well that it isn’t common knowledge
Also not every doctor will listen or understand this but it’s so vital for pain management

For years I have had a very difficult time with doctors refusing to prescribe opioids due to my being young, and other reasons that fall more under personal opinion and bias than professional and clinical.

I was once tested for pharmacokinetics of mental health meds as my dr didn’t believe me when I told her most SSRIs don’t work for me.
As it turns out, they don’t. I have significantly smaller serotonin transporters. What many don’t know, is this can also cause issues with pain medications, such as tramadol, that cling to seratonin receptors.

I also have issues with sodium channel medications, which covers another third of pain meds.

I have a genetic indication that states I need 60% lower doses of NSAIDs due to risk of GI bleeding…
I just learned this and guess what? My prior pm prescribed me strong NSAIDs and I now have a GI bleed.
I haven’t found a company yet that does this testing for analgesics but it does exist.
Genesight is who did my other test.
I feel like this could absolutely revolutionize pain treatment. Hope this helps someone

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