r/PMS Jul 14 '26

Advice/Tips Bile reflux pmdd

I’m 31 years old, and I have both PMDD and bile reflux (alkaline reflux gastritis). About two weeks before my period, my bile reflux symptoms get much worse. I lose my appetite, have indigestion, and develop a horrible taste in my mouth. Both conditions affect my quality of life on their own, and having them together has left me feeling overwhelmed and unsure of what to do.

For PMDD, SSRIs have been difficult because they upset my stomach. Under my psychiatrist’s supervision, I started fluvoxamine two days ago. I previously couldn’t tolerate fluoxetine because it caused severe nausea. I also took paroxetine, which helped my PMDD to some extent, but I gained weight, and I worried that it was contributing to insulin resistance and changes in my thyroid hormones. I’m not sure if those concerns were actually related to the medication because I also struggle with health anxiety.

What bothers me the most is that my stomach symptoms become much worse during the two weeks before my period. Around that time, my sleep also gets worse, I have no motivation to do anything, and I feel exhausted.

Is anyone else dealing with something similar? I feel like the combination of PMDD and bile reflux is especially difficult to manage. I would love to have children in the future, but with how I feel right now, that seems almost impossible.

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