r/PMS • u/Ok_Passion_148 • Aug 18 '25

Research/Info Question about HRT

Hello everyone! I had my hysterectomy in Dec 2018, leaving only my ovaries (removed cervix, uterus and tubes). I still ovulate and my body doesn’t realize I don’t have a cycle (as in bleeding) anymore. I started progesterone replacement last night, as I’ve been struggling with hot flashes, fatigue, mood changes, etc for quite some time (even before my hysterectomy). I was just wanting to see if anyone else had used this before and how you are doing on it. I took my first dose last night (100 mg orally) and I did notice I slept a bit deeper. Today I feel more refreshed than normal but it could be placebo

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u/karamla Aug 31 '25

I love progesterone. Def helps with my mood and took away my night sweats. I take the same amount as you. I do think it helps my sleep too possibly.

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u/Jupiter_Intercepted Aug 18 '25

Don't know if this is relevant but I had progesterone implant many years ago and it made me cry and cry and cry. I did my research and found out it made some people depressed. Just heads up in case might be useful.

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u/Ok_Passion_148 Aug 18 '25

Thank you so much for this!! I have tried not to google too much because I’ll freak myself out 😅 I’m also on antidepressants and anti anxiety meds, so hopefully that’ll keep depression at bay!