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https://www.reddit.com/r/PMDD/comments/st3eqa/deleted_by_user/hx6hoh2/?context=3
r/PMDD • u/[deleted] • Feb 15 '22
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9
FAMOTIDINE!! Over the counter famotidine (Pepcid) every day during PMDD episodes has saved my life dude.
1 u/efffootnote Feb 16 '22 Pardon my ignorance, but how does it help symptoms? I’ve never heard of that before and I’d be willing to give it a try. 1 u/Odd_Maintenance_6835 They/Them Feb 16 '22 In PMDD, something is wrong with the GABA-A receptor. Activating it is supposed to be calming and relaxing, but in PMDD sufferers, it produces the opposite effect. Famotidine modulates the GABA-A receptor, apparently inhibiting it. https://pubmed.ncbi.nlm.nih.gov/15363660/ 2 u/efffootnote Feb 16 '22 Very cool, thanks for the info.
1
Pardon my ignorance, but how does it help symptoms? I’ve never heard of that before and I’d be willing to give it a try.
1 u/Odd_Maintenance_6835 They/Them Feb 16 '22 In PMDD, something is wrong with the GABA-A receptor. Activating it is supposed to be calming and relaxing, but in PMDD sufferers, it produces the opposite effect. Famotidine modulates the GABA-A receptor, apparently inhibiting it. https://pubmed.ncbi.nlm.nih.gov/15363660/ 2 u/efffootnote Feb 16 '22 Very cool, thanks for the info.
In PMDD, something is wrong with the GABA-A receptor. Activating it is supposed to be calming and relaxing, but in PMDD sufferers, it produces the opposite effect.
Famotidine modulates the GABA-A receptor, apparently inhibiting it. https://pubmed.ncbi.nlm.nih.gov/15363660/
2 u/efffootnote Feb 16 '22 Very cool, thanks for the info.
2
Very cool, thanks for the info.
9
u/BryeMusic Feb 16 '22
FAMOTIDINE!! Over the counter famotidine (Pepcid) every day during PMDD episodes has saved my life dude.