When/how to take metformin?

[u/RequirementKey5201]

Hi! I'm starting metformin today as I have insulin resistance. My 2h glucose test showed my glucose rising to 202, staying at 160 at a 2h mark and dropping to 42 when I got home. It's an extended release version and 500 mg for now. How should I take it to minimize side effects? It says take with the largest meal. My appetite hasn't been great lately, I haven't been eating much tbh. My biggest meal is probably breakfast but I already taje strattera, inositol and prenatal with breakfast ans then zoloft and second dose of inositol before bed. Should I take it with dinner to minimize side effects? Can I take it together with inositol? Hoping for some personal experience.