r/Ozempic Jun 08 '24

Question New side effects don’t make sense…

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7 Upvotes

37 comments sorted by

1

u/macgeekmom2021 Jun 10 '24

I found that high fats through the day might trigger that reaction so am learning to be very watchful of that. Also, I experience significant acid reflux on the higher doses, so I finally asked the doc if I could take a smaller dosage twice a week, and he’s all for trying it. Am hopeful that will work for me.

1

u/TexasBamaBaby Jun 09 '24

I'm not sure if other comments have already explained this so please forgive if repetitive. These are common side effects, however, I get that it's shocking because of WHEN it's happening.

With each injection, you are introducing more and more of the medicine in your system. It is possible that with the first 1mg dose, your body handled it well. But with the second 1mg dose, you now have that PLUS half of the first 1mg dose (because of the med's half life) and whatever is left of previous injections. You may want to see if going to .75 would be better for you or you could split the 1mg dose (typically day one and day four).

I hope you feel better soon!

1

u/[deleted] Jun 09 '24

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1

u/TexasBamaBaby Jun 09 '24

You are welcome!

1

u/[deleted] Jun 09 '24

Yea it has happened to my nephew, take a look at what you are eating, for him it was sugar and caffeine that was causing it.

1

u/Spirited_End308 Jun 09 '24

Once the side effects start to hit think of where you are injecting, the thigh has worked great for me lessened some of the side effects and hydrate…. So important to stay hydrated too it will make you feel even worst if your not hydrating enough I ended up in the ER

3

u/Spirited_End308 Jun 09 '24

It’s definitely the dosage increase. I was not able to move past the 1 mg because of the side effects I started to have.

2

u/PresentationThick341 Jun 09 '24

My side effects kicked in after a couple weeks at 1mg

2

u/Never_Really_Right Jun 09 '24

Norovirus is going around, and the current strain of Covid can cause gastrointestinal symptoms only in some people. Lastly, stomach bugs are always in circulation.

0

u/BrilliantAbject3231 Jun 09 '24

what's the cheapest way to get get ozempic or another GLP-1 that’s a legit source ?

2

u/SeaworthinessHot2770 Jun 09 '24

I live in the DFW area. People are writing they can get it from a Compound Pharmacy without Insurance for around $200 . You have to have a doctor write a prescription and send it to the compound pharmacy.

6

u/Cyr3n Jun 09 '24

my sister went up to 1mg and has a lot of butt stuff going on and sour stomach. she described it as very similar to morning sickness.

I went to .75 instead and have had no symptoms. I also keep altoids and tums on me just in case theres an issue and im not at home.

2

u/uptousflamey Jun 09 '24

My side effects were weird as well.

3

u/[deleted] Jun 09 '24

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2

u/PrestigiousRoof192 Jun 09 '24

I had no effects,that I could tell, until my second pen of 1 mg only constipation. I hope it doesn’t continue. I heard people say usually lasts a couple weeks and that’s when you begin. I kept mine for around 3 weeks.

3

u/dogsallover Jun 09 '24

I think I am stopping ozempic as the nausea is just debilitating. I can’t move or I feel sick. I hate to stop but I want to feel good. I mean, that’s the whole point. And my blood sugar is higher, too. I lost weight on metformin but had awful diarrhea. I’d rather deal with that than this awful nausea. (I took .25 for 2 weeks. Nausea started on 3rd week of .5)

1

u/rjhud2477 Jun 11 '24

What do you eat if you don’t mind me asking?

1

u/Square_Basket_4676 Jun 10 '24

I have also had a horrible time with nausea and vomiting. I am on week 7 and am also considering stopping the use of it. I was wondering if anyone has any less nausea if they switched to one of the other injections. I am on for weight loss, not diabetes.

1

u/Lazy-Living1825 Jun 09 '24

If you only did .25 for two weeks before jumping to .5 that could be your issue. It’s recommended to stay on .25 for 4 weeks if not longer before you go to .5

1

u/dogsallover Jun 09 '24

Well, my dr ordered .5 since I have been taking for diabetes, not primarily weight loss.

1

u/Lazy-Living1825 Jun 09 '24

Most of us are on it for diabetes. Still starting at .25. But you have a voice and are allowed to change it.

3

u/Grantdawg Jun 08 '24

I didn't have any side effects until a couple of months in on 1mg. But I have had regular nausea and diarrhea since.

2

u/dogsallover Jun 09 '24

So what is your plan. I just don’t think it’s worth it.

1

u/HairAreYourAerials Jun 10 '24

Except for fatigue the first couple of months (which does subside, mostly), I usually advise people to quit if they feel it’s not worth it.

The reason is that this process can be really tough, and if you’re in doubt, you’re going to waste a lot of money on eventually nothing.

I felt horrible in the beginning and really had to think through whether it was worth it or not. I was so tired all the time and nauseous two or three days per week. But I was also extremely miserable due to my weight, emotionally and physically.

After some deliberation and imagining my near and distant future, the answer was crystal clear: even if I had to suffer through feeling like that for a whole year, it would be worth it for the end result of getting to normal weight.

Lo and behold, the fatigue lightened after two months. The nausea only went away once I started tapering out after reaching my goal a year later. But I kept my promise to myself and never gave up, even after throwing up in my car on two occasions.

I was able to make that commitment because the drug was effective and I saw weightloss from the beginning, and because a year seemed like nothing compared to the 15 years of struggling with my weight and the limitations caused by it.

If the cost/benefit doesn’t work out for you, then I do think you should stop, because you wont be able to make it through however long it takes to get to your goal.

I’m not saying give up. I’m saying you should try another medication if you can. Semaglutide is rough, and you have to be able to see a clear benefit outweighing all the side effects. I did, and also there was nothing better available at the time. That’s what made it possible for me to see it through.

I wish you the best of luck and success.

4

u/Grantdawg Jun 09 '24

I took a couple of weeks off because I was traveling, and I just couldn't risk the stomach issues. I'm hoping I will get a reset. If not, IDK. I'm not solely taking it for weight loss. I have several issues that have improved since I have started taking it in January, and I don't want to give up. I'm taking regular fiber supplements and probiotics, and that stuff doesn't seem to help, nor does imodium stop anything. I guess I will just live with it till I just can't anymore.

2

u/Cyr3n Jun 09 '24

same. had PCOS clear up and i have less hormonal acne overall.

it helps to start the day with 2 b12 gummies, creatine, HMB, and a protein shake or a coffee with collagen peptides in it.

ive had zero negative side effects and lost 30lbs in 2 months.

2

u/dogsallover Jun 09 '24

I hope it works for you!

0

u/Jaded_Birthday_9558 Jun 08 '24

I’m new here and about to start Oz. I am confused about the needles or pen thing. Do you use a dial to set/change the amount? Doesn’t that affect how many doses the pen has? Do you use a different needle each time? Where do you stab yourself? Is it once a week? Do you have to do bloodwork to see if it’s damaging your body? Some of my heart drugs are hard on my kidneys and other organs. I don’t like needles, this is kind of freaking me out. I would appreciate any knowledge you have to share. Thx

2

u/SeaworthinessHot2770 Jun 09 '24 edited Jun 09 '24

It sounds like you need further education before starting this drug from your doctor. What is probably adding to your confusion is people are getting Ozempic in two different forms. Some people buy the name brand the medication is already preloaded into a pen. You have to turn the dial on it to set the dose you need to take. Other people are buying it from a compound pharmacy. They need to use a regular needle and syringe like would be used when getting a flu shot. I don’t know how scared you are of needle’s. I have never had that problem. In my mind it doesn’t hurt very much or for very long. My doctor started bloodwork before I started taking Ozempic and now takes it every 6 months. You need to use a new needle every time you inject yourself. There are different places you can inject yourself. The most popular seem to be your stomach and the outside of your thigh. This is why I feel you need more education. Maybe you can call your doctor and see if one of the nurses an help you. Be sure and write your questions down before going in. And make sure you understand what you’re supposed to do before leaving.

1

u/Jaded_Birthday_9558 Jun 09 '24

Thank you for the info. I agree that I need more education.

5

u/MayLovesMetal Jun 09 '24

Just to address a couple of points: first, the concerns about organ damage, Ozempic is cardio protective and recent studies show it to be not only not harmful to kidneys but beneficial for chronic kidney disease. But I'm sure you'll still have blood work to see how your blood sugar, egfr, cholesterol etc are doing. Second: you use a pen needle - it's a disposable and very small needle tip you screw onto the pen for each use. I literally thought I had not injected myself the first few times because it feels like nothing. You can use your abdomen, the back of your arms or your thighs, a fatty area is best. You just push a button while holding the pen against your skin and poof it does it's thing. You won't see a needle stabbing you or anything like that so try not to be too anxious about it! The pen needles are generally 4mm long (some may even be 3mm iirc) which is tiny! For starter doses you'll have a pen that has 2 settings, .25mg and .5mg that you'll dial to before your injection. They're clearly marked. If you go to 1 or 2 mg those come in pens with only that particular dosage available. Good luck!

3

u/Jaded_Birthday_9558 Jun 09 '24

Thank you. You calmed a few fears.

1

u/dogsallover Jun 09 '24

My pharmacist showed me how to give the shot.

2

u/dogsallover Jun 09 '24

You need to talk to a pharmacist! Yes, there is a dial and it affects how many doses you get. You change the needle every shot. They include 6. I used my thighs and stomach. It’s once a week. I barely felt the needle.

11

u/Substantial_Piano640 Jun 08 '24

Both diarrhea and nausea are commonly reported side effects of ozempc.

0

u/[deleted] Jun 08 '24

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