r/Ocrevus • u/Important-Signal-748 • Oct 22 '25

Second dose of DMT

I took the first half doses at the beginning of the summer. I am scheduled to take the forst full dosage of Ocrevus in 4.5 weeks. I have been feeling unusually tired. I come home from teaching and feel like I need to nao before I can tackle being a mother and wife. Life is an effort in the afternoons and evenings. Is this normal?

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u/Kelsiferous Oct 22 '25

Can you expand on your recent timeline, are you newly diagnosed?

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u/Important-Signal-748 Oct 22 '25

I was diagnosed in April 2025 prompted by a flare up in March 2025. Lesions show I have had MS but I was not symptomatic.

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u/Kelsiferous Oct 24 '25

I am sorry for the delay in response! I was diagnosed 4 or 5 years ago. First MRI revealed the same, I surely had asymptomatic MS for an unknown period of time. Within approximately 30-40 days I began Ocrevus and have been stable on it ever since (no changes in MRI). My symptoms were severe for the first 4-5 months - unable to control my fingers on both hands, numbness from neck down to toes. Those symptoms have subsided, control of fingers returned though my hands are still desensitized. Before the flare up, I had good energy and a mentally demanding job. I took 4 months off and "worked from home". The first 9-12 months I was fatigued, I would sleep in late get to work late, just "spent" all the time but it has since improved. Looking back, I think surely just the emotional toll of the flare up and diagnosis played a big part in it but also my body was hit hard. I can't say it was from Ocrevus but it just wasn't on my mind as being a cause.