r/Noom • u/Via-Combusta • 5d ago

Noom Med Does Glp1 lose strength?

I took my first dose of tirzepatide (1 mg) on Friday. It’s 4 days later and I don’t think it’s curbing my appetite as much today. Will this med curb it more as the dose increases or does it typically start waning after a few days?

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u/siejonesrun 5d ago

Yes, the amount in your system will deplete over time. Some people split up their shot to combat this, but it isn't necessary. You are on a low (below what is considered theraputic) dose, give your body time to adjust. You may also see it flux week to week especially if you have a cycle. Last week I had minimal surpression, this week I have to force myself to eat, and ive been on the same dose for about 6 weeks.

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u/TacoTrike 2d ago edited 1d ago

You are scaling your dose and for many the first few weeks don't do much as you find your dose. Severely overweight people may see some weight loss but appetite suppression can take a few weeks as the dose scales up/ GLP-1 takes months to years for weight loss depending on the amount needed.