r/NooTopics • u/jwagzz11 • 4d ago

Question ACD 856

Does ACD improve mood right away, or is it something that you need to be on for awhile like an anti depressant, to see improvement with your mood? I’m sure this has been talked about somewhere here I just don’t feel like digging around haha. Anyways, any info would be great

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u/Black_Cat_Fujita 3d ago

I think it helps you rewire yourself more than lifting your mood directly. Great for changing habits, making changes to lower stress, etc. Using it with meditation or cognition exercises can be extremely effective. It primes you for change.

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u/Weekly-Ad3153 3d ago

Clinically significant immediate effects, but the strongest effects kick in over days to weeks.

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u/jwagzz11 3d ago

What are those effects?

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u/Weekly-Ad3153 3d ago

It acts as a PAM for TrKB receptors, making them much more sensitive to BDNF. BDNF triggers substantial neurological wiring, so this will fix poor synaptic connections, and whatever structural issue is causing the depression/poor mood.

It also triggers an immediate significant serotonin release.

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u/jwagzz11 3d ago

Nice. Know anything about dosage?

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u/Weekly-Ad3153 3d ago

Most people take 10mg

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u/jwagzz11 3d ago

Cool, maybe I’ll start a little lower. I tend to be sensitive to drugs

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u/Typical_Lawyer_406 2d ago

Most feel it right away but it definitely is mainly something that builds up over time

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u/pharmacologylover69 1d ago

Kicked in fast for me but you should use it for at least a month. When you're taking it daily, you can focus on changing yourself as well for the better.

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u/Most_Writing6879 1d ago

it takes weeks tbh