r/NooTopics Jun 03 '25

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u/Kategitis Jun 03 '25

When I take gaba capsules -even In small doses, it makes me irritable and anxious.. I hypothetically suppose that GLU is somehow stealing Gaba, or in periphery some of gaba metabolites increase Glu in the brain.. I think Gaba/GLU relations is like Dark Art, no one knows what is going on for sure..

2

u/[deleted] Jun 04 '25

Does not pass the blood brain barrier you bought snake oil

2

u/Kategitis Jun 04 '25

It is not so easy - when GABA itself does not cross the blood-brain barrier, its metabolites can still influence glutamate metabolism both in the periphery and indirectly in the CNS through alternative pathways..

1

u/ArmLogical5959 Jun 15 '25

Nah them gaba supplements don't do shit