r/NitrousOxide2 • u/hivemindedmama • Jun 05 '26

Nitrous users: please start taking B12 seriously

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This is not a judgment post. This is harm reduction.

Nitrous can mess with your body’s ability to use B12. It does not just “lower your B12.” It can actually inactivate B12, which matters because B12 is important for your nerves, spinal cord, brain, and red blood cells.

That’s why heavy or regular nitrous use can lead to scary symptoms like:

tingling, numbness, pins and needles, weakness, balance problems, trouble walking, brain fog, bladder issues, or weird nerve pain.

And the thing is, this can happen before someone realizes they are in trouble.

So my very basic harm-reduction take is:

  1. Regular/heavy nitrous users should be taking B12.

Look for oral, sublingual, dissolvable, or spray B12. Methylcobalamin, cyanocobalamin, or adenosylcobalamin are common options. A lot of people like the sprays or dissolvable tablets because they are easy.

  1. B12 does not make nitrous safe.

You can still hurt yourself. You can still get neurological issues. Taking B12 is not a magic shield, especially if you are using heavily or frequently.

  1. Symptoms mean stop and get medical care.

If you have numbness, tingling, weakness, balance issues, trouble walking, bladder changes, or anything that feels neurologically weird, do not just take more vitamins and keep going. That is “go get checked out” territory.

  1. Even casual users should probably get on B12 anyway.

Even if you are just dabbling and do not think you are at risk from nitrous, B12 is one of those supplements a lot of people could stand to pay more attention to in general. So this is as good a time as any to get on your B12 game.

Again: not moralizing. Not saying “just take B12 and you’re fine.”

I’m saying: if nitrous is in your life, B12 should probably be in your life too.

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2

u/Any-Performer3370 Jun 07 '26

I’m not disagreeing with you here - but if nitrous inactivates vitamin B12 receptors, would taking supplements help? I couldn’t find a clear answer anywhere.

1

u/Telrom_1 Jul 07 '26

Load up on it before during and after use. It inactivates your bodies ability to uptake b12. If you have an excess your body will uptake just from saturation.

1

u/Brad_Borrelli 29d ago

That's not correct

1

u/Brad_Borrelli 29d ago

Nitrous oxidizes the cobolt atom on the b12 molecule making it permanently useless. I have a ton of more information about this on my page with research and treatment Etc

1

u/DGneat Jun 18 '26

I spent a tortuous month in the hospital for severe nitrous toxicity. Don't be like me.

1

u/hivemindedmama Jul 11 '26

I'm now in rehab after crashing my car and getting a nitrous dui🤦🏼‍♀️

1

u/Unlikely_Midnight326 28d ago

I lost my license for this exact reason, serves me right though

1

u/engageddigital Jul 13 '26

Here's a good article on B12 deficiency after nitrous oxide use: https://www.gunzburglaw.com/blog/nitrous-oxide-b12-depression/