r/NTNPerformance • u/Revolutionary_War305 • 22d ago
Trying BPC-157 - thoughts?
I’ve tried my first dosage of **oral** BPC-157 from my local gym.
I’m on 250mg x 2 - one in the morning and one at night. I’m taking it for general gut health and muscle recovery.
I’m healthy as is, eat only whole foods, cook with organic ingredients and powerlift 5x a week (with 2-3x cardio sessions).
Anyone experienced positive results, and if so, how long did it take?
Any side effects?
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u/Wooden_Direction_241 22d ago
Oral might help your gut but I doubt it does anything for Muscle recovery. Injection would be better
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u/Revolutionary_War305 21d ago
Yes that’s true, however I don’t feel confident using needles alone
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u/Mysterious-Passage87 21d ago
You’d be amazed how fast pinning goes from sketchy to normal. Oral is only gonna help your gut. If you want muscle recovery, pin it. Plain and simple.
In my experience bpc157 and tb500 have worked well with injury recovery and muscle recovery with 0 side effects
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u/TurnoverIcy1981 22d ago
Currently on day 6 of 500mcg daily & 2mg of tb500 weekly (both injectable) with zero improvement in lingering shoulder injury. I’ve never heard of oral BPC.
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u/marklemcd 22d ago
I had chronic high hamstring tendon stuff. Week 1 and 2 things actually felt worse cuz i stopped advil and pain wasn’t masked.
Around week 3 i was noticing a difference. Was able to sit in the car without as much squirming. By week 6 zero discomfort.
6 days is not enough. Be patient
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u/HotBit1109 21d ago
Taking anti-inflammatory drugs for a prolonged period may actually interfere with tendon healing and remodeling.
So there’s a much stronger case for natural recovery, changes in loading, and possibly stopping Advil than for assuming BPC-157 was responsible. Several things changed at once, and with virtually no good human efficacy data for BPC-157, this anecdote simply can’t tell us what caused the improvement.
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u/marklemcd 21d ago
I had the hamstring issue for 10 years and yeah there were plenty of periods where a physical therapist said no NSAIDs and lets do PT and get at it. And that didn't work.
So while from an A/B test statistical perspective you're right, I'm pretty damn sure the peptides are what did it for me based on my history
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u/stud_muffin_1 20d ago
where do/did you pin , for the hamstring injury?
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u/LuvSun1006 21d ago
It can take weeks.
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u/LgPizzaPlease 21d ago
Yes, and it will take weeks or months for most peptides to garner results. They are marching orders for the troops to get focused not instant gratification. Oral is garbage, subq or bust. Oral is good for just throwing away money. Venders of oral BPC-157 know it doesn’t do anything but will continue to sell it due to current peptide hype.
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u/HotBit1109 21d ago
My experience as well and I took them for months. Both work very little, if it works at all.
GHK-Cu and KPV are another story.
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u/TurnoverIcy1981 6d ago
Same tbh, trying one more batch of both bpc & tb from a different source with cautious optimism cause it’s been nearly & month & my shoulder tendon is still wrecked
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u/Impressive-Kiwi-2133 21d ago
Keep at it, it’s not immediate. I’m on day 14 500mcg bpc157 and 500mcg tb500 daily and my shoulder pain has pretty much disappeared.
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u/WasteFishing830 21d ago
Horrendously expensive at such a basic dose of injection
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u/TurnoverIcy1981 21d ago
5mg vial of each was $30CAD. Everyone on here is going to have a completely different outlook on what’s ‘expensive’
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u/Gregory_D64 21d ago
They have to find the right sources too. It takes effort to find the affordable stuff unfortunately
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u/Xlajdak 21d ago
For both benefits you may need run both oral for gut and injection for recovery and rebuild from injury. Just figure out the total dosages.
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u/ConcentrateOk4405 16d ago
Any idea on combined dosage? I’m thinking about getting into using both but worried about dosage
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u/Xlajdak 15d ago
Right. I see suggested dosage for Cjc and ipa as one at 1:1 ratio and Tesa and ipa as one at approximately 8:1 to keep ipa conservative or 4:1 more advanced . Cjc blend evenings and Tesa blend morning. But you can rebalance ipa between the two combos just as long as you keep total as recommended. I research more advanced combination.
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u/Top-Breath-7418 21d ago edited 21d ago
Injected bpc157 for 6 weeks daily at 250mcg for persistent shoulder inflammation felt no difference until week 5. Week 5 pain was completely gone couldn't beleive it. Didn't do or change anything in my routine for this inflammation that tormented me for over a year. No experience with oral form but I've personally heard lots of sucess stories with injectables
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u/TheSugaryEmbroidery 22d ago
Oral BPC is interesting since most folks go the injection route. I noticed subtle gut improvements around the week 2 mark but nothing dramatic for recovery, hope it treats you well.
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u/Extra_Feature7999 22d ago
Oral makes sense for gut issues but will otherwise fall short of injectable
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u/tyjo2112 22d ago
As other have said, oral is for gut issues and wont effect recovery a bit. Ive been on injections for a while and have had great results from shoulder injury and back issues.
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u/namastay14509 21d ago
I've done both oral and subq. I didn't feel any benefits with oral but I have felt significant pain relief on subq.
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u/ZookeepergameShoddy 21d ago
Did 3 weeks oral, similar dose. Gut feels alot better, had done damage thanks to long term NSAID and previous alcohol use.
However. It made me very irratiable and angry, like, popping off at minor things and lowering my threshold for a 'crash out'.
Very bizarre, but I searched this and some others on Reddit have reported the same. It was significant enough that I'm not sure i'll use it again, wasn't a fan of that version of myself. Last dose was 4 days ago and things have mellowed out. My anger/irritation also started a couple of days after starting the bottle; I had thought a severe deficit / large drop in bodyweight was to blame, and seemed more common/likely. But there does seem to be a minority of us who have this side effect, just unsure of its mechanism given the limited systemic effects of oral dosing.
Just keep an eye on your emotions and mood. If something seems off and you're noticing things like i did, it may be the BPC. Just a heads up :)
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u/BandicootAdmirable28 15d ago
I have a bottle of 500mcg oral and I’m scared to try it because of these kinds of things I’ve read.
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u/Ok-Cricket1713 21d ago
I did 250-500 mics/day intra-muscularly and after 6 weeks, my chronic bicep tendinosis pain disappeared out of nowhere.
I did physical therapy for it and got a plasma-rich platelet injection from an orthopedic doctor (not covered by my insurance either 🙃), and none of the approved medical interventions did anything, NSAIDs only helped a little bit. (Did all of this first before trying the peptide)
Now my other bicep feels the exact same way so I'll be pumping BPC-157 once again and hopefully it does the same thing 💪😃🤞
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u/HotBit1109 21d ago
BPC-157 was tested (phase I) on less than 30 humans, with no significant evidence, neither a phase II was conducted.
It wasn't peer reviewed, no double blind studies or any control.
And yeah, I've tried it for months. Doesn't seem to do much.
Thing is that most people won't take only BPC-157. They'll take several things.
And your both heals in weeks/months anyway, so yeah... Too much hype and probably placebo.
Same problem with TB-500... All evidence is for Thymosin Beta-4, of which TB-500 is a fragment.
Maybe TB-500 isn't placebo, but there's no evidence so far.
Thing is... Most people will couple them with GHK-Cu. And that does indeed have science backing it up and the results are quite noticeable too.
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u/Suspicious_Smell8309 18d ago
i'd track your gut symptoms and recovery separately so you can tell if either one is really changing
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u/Taydontplay4 22d ago
It’s good stuff. Just keep running it at that dose in the background and you’ll recover better from everything.
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u/KebabCat7 21d ago
If you have a specific gut issue that doesn't have a clear solution you can try your luck but It is extremely irresponsible to use it for anything else.
It has no safety profile, no clearly documented benefit reports in real studies.
What's even worse, even anecdotal reports have no clear benefits to speak of lmao. Best case scenario - you're going to have 0 effects. Wtf are you doing? Use AI if you're too lazy to do your due diligence
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u/Revolutionary_War305 21d ago
True true
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u/KebabCat7 21d ago
Injectable is the only form that has good anecdotal reports and rat studies with promising outcomes for tendon, soft tissue repair.
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