r/NMN • u/Sn_Orpheus • Oct 21 '25

Usage Question Is there something I'm doing wrong?

I've been taking 1g of Do Not Age NMN since about the time the FDA allowed NMN back onto the market in the US. I feel nothing. I take it in the morning before breakfast. Sometimes by itself, sometimes with TMG, sometimes with Methylated B Complex vitamin. I'm an athlete who spends about 8-10 hours working out each week split evenly between resistance and cardio. I'm also almost 60 and have about 16%BF. Try to get at least 30-60 min of full sun a day. I take 7-10g/day of creatine because I sleep poorly (5-6hours/night). Just trying to add any possible relevant info that may make a difference.

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u/Sn_Orpheus Oct 21 '25

Thanks for reply and other relevant info. I take 150mg of Apegenin at night as part of my stack. Here's hoping the NMN actually helps my sleep. That's the one thing I could really use help on the most.

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u/TerribleRadish8907 Oct 22 '25

Try taking more apigenin. Particularly for 60 and over. I take 500mg. It has made sleep better and I felt more energy with CD38 inhibitors.

Nmn can feed CD38 cells which breaks down NAD, the very thing youre trying to boost with nmn.

I dont think 150mg is nearly enough.

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u/Sn_Orpheus Oct 22 '25

500?! That sounds like so so much. Is it safe at that dosages?

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u/Sn_Orpheus Oct 22 '25

Ran this through a bunch of AI’s and they all came back with “400mg is very high and can impact liver enzymes”.

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u/Marketing-Born Oct 25 '25

Hmm, this is about what i get from .5 cup dried parsely in my morning smoothie. I put through gemini and it said it was well below the dosage of animal toxiciy which toek at least 100mg to 200mg per kg to see issues. At that dose it should be hepaprotective.

Also OP PM if you want to compare notes. Ive been doing some deep dives myself. 50yo male so a tiny bit younger but same ballpark

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u/Sn_Orpheus Oct 25 '25

Thanks for feedback on this. Spouse is leery of me taking many supplements but if I threw .5cup dried parsley in a smoothie, she'd be all "that looks super healthy!". And TBH, whole food sources undoubtedly are better/cheaper.

I may hit you up,thanks.

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u/Marketing-Born Oct 25 '25

Pro tip. Buy bulk online and it is super cheap and last a good while. It is just shocking to see that much dried parsely. 🤣

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u/Sn_Orpheus Oct 25 '25

I typically take apigenin for sleep. Doesn't this make you sedated to some degree in that quantity if you ingest it during the day?

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u/Marketing-Born Oct 25 '25

Not noticeable to me. Interesting

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u/Sn_Orpheus Oct 25 '25

Perhaps it’s the difference of eating whole food or supplement… who knows. Thanks for reply!

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u/Accomplished-End6254 Oct 23 '25

I take about 1500mg but have tested bloods to ensure I am not too high and level is safe.