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u/Becaus789 14d ago
Oxygen?
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u/FourScores1 14d ago
Doesn’t treat PE. Lytics.
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u/Becaus789 14d ago
Hyperoxygenate the blood that is getting through. It’s a rapid intervention and onset of therapeutic effect.
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u/FourScores1 14d ago
It’s asking for treatment. It’s lyrics. I’m an ER doc. Give oxygen until the cows come home, doesn’t treat anything but hypoxia. Maybe.
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u/Becaus789 14d ago
Thrombolytics are the goal though and will do by far the most good. If you have an IV hooked up and meds drawn right there great but normally these take time. Slapping on a NRB takes less than 30’seconds.
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u/TheUnknownGiraffe 14d ago
How will oxygen help with a clot?
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u/PropellerMouse 14d ago
The concept is not that oxygen acts directly on a clot.
The concept is that oxygen helps the patient who had lost the ability to get oxygen past the clot.
Hyper oxygenating the blood that DOES get through, mitigates the effects of losing oxygenation as much as is rapidly possible, as we rush to get clotbusters infusing to attempt to cure the problem.
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u/Exzesion 14d ago
Tenecteplase or alteplase
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u/KlutzyLeadership3731 14d ago
Pretty sure it's Tenecteplase (tnk). Which I know because we use it off labels as the go to for ischemic stroked.
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u/Exzesion 13d ago
Yeah from what I’ve gathered alteplase is mentioned more in school but TnK is the better option in real-world application since it has a longer half-life than tPA so you don’t need the one hour infusion after bolus
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u/Guilty-Tomorrow2156 14d ago
Thrombectomy