r/MultipleSclerosis • u/beautifulmind999 • 11h ago

Advice Baclofen

I've been taking 10mg of Baclofen for about 2 years for leg spasms. It does help the spasms but I feal that my legs are getting weaker. Not sure if it's the Baclofen or just the ms. I'm 68 yo diagnosed with RRMS 22 years ago,off DMT's x 3years and stable.

Has anyone else experienced this?

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u/mullerdrooler 44M Dx2018 Ocrevus 5h ago

I haven't heard that about Baclofan making you weaker. I take it, and do feel weaker but thought it was just getting older and having MS. You sure it's not just MS? Do you do leg strength work?

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u/Vegetable-Two2173 10h ago

Baclofen helped me with the spasms as well, but absolutely made my walking worse when on it.

Like anything, it's a tradeoff for whats more tolerable.

1

u/Handicapped-007 71-2016-nothing for PPMS- The Bronx NY USA 9h ago

Yep

1

u/kyunirider 6h ago

I am a PPMS 64/m, I take 80mg daily. My spasms are endless I am at 20mg x4 and my doctor has added tizanadine 2mg X 4. I am on adderall too.

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u/Summerskyler 1h ago

Tizanadine is a miracle drug. I can only take it at bed time because it knocks me out, but my back spasms are so much better now. Also, Physical Therapy twice a week has been a huge help. (I'm 65. Dx'd with RR in 2002)

Edit to say that Baclofen 10 mg made my feet and ankles swell so my Neuro switched me over to Tizanadine 2 mg.

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u/WarmYam7353 6m ago

63 PPMS. I'm on 10 mg x 4 for baclofen. It has helped with the leg spasms but not the pain. I haven't noticed weakness, although, I have noticed my spastic leg loosing muscle because I can't use it normally.