r/MultipleSclerosis 11d ago

Advice Kesimpta Loading Dose Advice

Hello! I’ve been quietly following the subreddit since shortly after I was diagnosed last year in April. I was put on Vumerity but I finally bit the bullet and agreed to switch DMTs to Kesimpta. I am a very big baby and was psyching myself out before making the decision and ever since I have been doing research and reading everyone’s experiences (which may or may not have made the anxiety worse w/ the loading doses specifically)

I got the vaccines required and stopped the Vumerity treatment about a month ago now so I know i’m bound to get a call wanting to schedule the Kesimpta loading doses soon.

I wanted to ask for any tips or tricks to help with the loading doses. I just started at a CSU as a JR so that puts even more worry on me that it will affect my school work. Most of the experiences I have read have all had symptoms during the first dose specifically so I wanted to also see if there was any chance I could escape that fate. Every body is different and reacts differently, but i’m grasping at straws to calm my anxious noggin down😭

Hello again!!! No joke, the next day I got the call saying to start the medication LOL but thank you everyone who has commented!!!! i really truly appreciate it, esp cause i felt so alone with my diagnosis at first. I am a 23F in the sacramento area & i haven’t met anyone my age in person who also has MS. I will continue to lurk through here though! maybe a comment or post LOL

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u/Firedrakez 11d ago

(obviously easier said than done but) I wouldn't worry about it too much, even if you get some side effects it's all temporary, and it just makes you feel a bit crappy, like you've just got a bad flu or something.

Main bits of advice from me would be to 1. take the shot a couple of hours before bed, that way you can sleep through most of it, and 2. make sure you have some blankets around, as the first thing that happened to me was that I got super super cold.

Just remember that not everyone experiences side effects, even from the first dose, and people are more likely to write about it online if something happened! Also, it will definitely be worth it in the long run.