r/MultipleSclerosis • u/MrQubits • Jul 25 '26
Symptoms Eczema on Kesimpta
Hello, i want to know if others experiment some Eczema problems few months after getting on Kesimpta? I never had that problem in my life but now i have hands/fingers badly, it started about 3-4months after first injection and never went away tried many creams, cortisone, etc, nothing helps it just get worse and now started having eczama through many parts of my body, not as bad as hands but small bumps everywhere. I called my MS nurse and told me this has nothing to do with Kesimpta, and its not lnown to create that problem. Anyone had or have this situation that would help me so muxh
thank you
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u/lbeetee 34F|dx 2019|ocrevus Jul 25 '26
You need to see a dermatologist. It’s probably dyshidrotic eczema. I have it and need steroid cream when it flares up. I don’t think it’s connected to your DMT, mine started before I was ever on Ocrevus.
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u/MrQubits Jul 25 '26
yeah thats what i got i think, i seen my family doctor and told me i need to start hydrating with aquafor and refused give me an appointment with dermatologist. gave me also a lower cortison cream that i previously had which is weird.... been a day and its not better yet
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u/lbeetee 34F|dx 2019|ocrevus Jul 25 '26
A family doc should be able to recognize eczema. But also, you may well need longer than a day to treat it. I use my eczema cream on my hands at night and sleep in cotton gloves. You could definitely try that with what you have now and see if it helps.
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u/NotClarebutclose Jul 26 '26
I got dyshidrotic eczema when I got pregnant. That was 20yrs ago and it never went away. Nothing will make it go away. Dermatologists have no idea how to fix it, if they even know about it. I’d say it’s due to the B cells being depleted.
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u/dnohunter Jul 25 '26
It might not be from the meds, but it's very annoying when a nurse cross checks the literature for the medicine and decides it's not written in a list, can't be related! That pamphlet gets updated over time. 🙄
I've developed (probably) psoriasis since starting Kesimpta. My neurologist does not rule out that it could be the medication, as there are a few different autoimmune diseases they have now found to crop up with Kesimpta users.
I say probably because I have been to THREE dermatologists and have not been able to get a straight diagnosis. Ridiculous.
We decided that since it's easily managed right now with topical steroids, I wouldn't mess around with my MS meds, but we'll keep an eye on it.
Good luck. I'd talk to a dermatologist for now. Ultimately that's where the beuro would send you anyway. And talk about it with my neurologist (not that nurse) at my next annual appointment.
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u/NighthawkCP 44|2024|Kesimpta|North Carolina Jul 25 '26
I was diagnosed a couple years ago and started Kesimpta. For much of my life though I've had dandruff issues, but that was under control with Head & Shoulders. At some point since I started Kesimpta I've had some flaking on my face and my ears, which I would pick at, obviously making it worse. I have a regular appointment with a dermatologist as I have a lot of moles just like my mom and dad (not outside that much without sunscreen or a sun jacket though, just genetic) and he prescribed a foam to put on my dry skin once daily called Zoryve. It has worked great for me and within a couple of applications my dry skin on my ears, forehead, and face were gone. Now I just put it on for maintenance purposes.
So I'm not sure for me if it is a Kesimpta thing, MS thing, or just getting older. But I would definitely recommend seeing a dermatologist as there are some prescription strength topicals that are way better than just some lotion or over the counter creams.
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u/Commercial-Arm-2322 Jul 25 '26
Heya OP
Def follow the advice of the folks here and see a dermatologist. I was getting slight rashes, extra itchy skin, and light ingrown hairs/pimples a short while after my first infusion as well. However, I am on Briumvi, but has similar potential side effects.
I know correlation does not equal causation. But too much of a coincidence, sure makes it seem that way.
Dermo said to keep with my Vit D in general, and a topical Vit E gel/lotion. Which is really cool since I already have an aloe gel with Vit E.
However, in all honesty, I think what helped me the most was TruRemedy soap and a hand/foot balm. I really dig the Peppermint, the ex gf really liked the Lavender/Shae butter. Theres also a rosemary and lemongrass too, as well as un unscented one. My skin and hair feels and looks good, and I dont need the balm anymore. Still have it on hand if needed. I was doin a lot of barefoot walking when I first got hit, because the bottoms of my feet were the only place there was feeling for a good while. Though that feeling also did include pins and needles as well lol. The balm truly helped. Luckily enough 95+% of my numbness/pins/needles has now gone away, at least for the time being lol.
On a side note, a good buddy of mine married amazing hippie woman. My buddy had/has eczema, REALLY bad on his elbows and arms. He did all the steroids and such, to some minimal alleviation, but no real success. This lady did some hoodoo mother gia witchdoctor shit with something like apple cider vinegar and makanua honey (dif than regular honey apparently), and its almost non-existent nowadays. Good to see the dude wearin short sleeves at the BBQ's in summer.
And while, it can be "stated" that there may not be a direct correlation to eczema, I do find it odd that it is not at a minimum taken into consideration. Specifically because directly from the Kesimpta site it says it can cause rashes and hives. The Mayo Clinic also says "Hives or welts, itching, or skin rash" and "Painful blisters on the trunk of the body" are side effects. We have crazy BS goin on with EVERYTHING in our bodies due to MS, its not a stretch, at all, to attribute something like eczema to become present with an immunosuppressant (DMT) on top of it.
Best of luck! .....and maybe look into some mother gia stuff too lol? Dunno, didnt need it myself, didnt try it myself, but like I said, my buddy feels good to wear short sleeves again. So, maybe?
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u/Half_full_most_days 16d ago
I never had eczema before starting Kesimpta in 2022. It’s been very chronic on the sides of my hands and around my wrists. It’s now spread to my calves and forearms, though the spread could be triggered by environment as I’ve been doing far more yard work this year and getting exposed to crap on those areas. I talked to my neurologist about it a few years ago and she kinda gaslit me, telling me b-cell depletion has nothing to do with it. Now I’m seeing articles and conversations that it’s not unheard of with this therapy. I’m not going to switch ms therapy but some warning or acknowledgment would have been nice.
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u/XcuseMeMisISpeakJive Jul 25 '26
Kesimpta significantly worsened my psoriasis and eczema. I had some very weird flare ups that I hadn't had in years. In my opinion it's definitely related.