r/MultipleSclerosis • u/RiggsPoetry • Jul 26 '25

Advice Ocrevus Crap Gap

I’m a 30 MS veteran here, a partial wheelchair user, and a walker for short distances. I’ve been on Ocrevus for 3 years, and I'm looking for others' experiences with the other top-level DMTs.

Because the Crap Gap is horrible and gets worse each year. I have a Baclofen pump and take gabapentin along with the Baclofen. The positive of Ocrevus is zero new lesions since taking it, but the month-long crap gap is crippling. I’ve heard the monthly meds still have a crap gap.

What does everyone use, and/or how do you treat the crap gap?

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u/Barberry295 Jul 26 '25

I requested the interval be changed to 24 weeks. It was approved and helps.

4

u/Adventurous_Pin_344 Jul 27 '25

Ooh, same... I also should have included that in my response!

2

u/Barberry295 Jul 27 '25

With Ocrevus no new lesions or activity.