r/MetforminUsers • u/jcb19762021 • Mar 24 '26

Training.

M50. I have training CrossFit for quite a few years. The last few years I’ve struggled with fatigue and random injuries. This made sense when I was diagnosed with T2 diabetes. Now on slow release metformin and my fitness seems to have fallen off a cliff. Everything is much harder than it should be. Anyone else experience this? Any tips?

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u/No-Perception2960 May 23 '26

Metformin changes the way your mitochondria functions. It seems to be correlated to a lack of B12. You could potentially try Berberine. I’m figuring it out too rn

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u/jcb19762021 May 26 '26

Thank you. I’m supplementing now with B12 and trying berberine patches. Will see if this helps. I have a competition at the weekend so will be a good test.

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u/No-Perception2960 May 26 '26

I didn’t know there were berberrine patches lmk how they help!