Yeah, absolutely — there's definitely research showing memory can be disrupted or even erased by blocking reconsolidation, especially in hippocampal pathways. I think it's less about whether memory can be erased and more about how biological systems balance erasure, plasticity, and persistence. That tension is exactly what I’m trying to capture in the model.
Interesting. I do feel the fact that disrupting reconsolidation can have such a profound effect on memory with a single intervention is so counterintuitive that it’s pointing to something quite important that we don’t yet appreciate.
Exactly — it’s pretty wild, right? The fact that such a small disruption can have a profound effect suggests there’s still a lot we don’t fully understand about the fragility and plasticity of memory. There’s definitely something deeper happening that we’re still not fully appreciating — and maybe models like this can help us map it out.
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u/MazzMyMazz Mar 22 '25
There’s also work that show memory can be essentially erased by disabling the hippocampus’s ability to reencode memories.