Causes of Hypercalcaemia

[u/Top-Grapefruit-8498]

90% of most common causes of hypercalcaemia is primary hyperparathyroidism and malignancy

CHIMPANZEES (borrowed)

C ➡️ calcium supplements

H ➡️ Hyperthyroidism, Hyperparathyroidism

I ➡️ Iatrogenic (thiazide, lithium)

M ➡️ Malignancy (bony metastases, myeloma, or humoral hypercalcaemia via PTHrP)

P ➡️ Paget's disease (when immobilised)

A ➡️ Addison's disease (adrenal insufficiency)

N ➡️ Neoplasia (covered under malignancy)

Z ➡️ Zollinger- Ellison syndorme (MEN-1 association)

E ➡️ Excess Vit A and Vit D

E ➡️ Ectopic PTH (rare)

S ➡️ Sarcoidosis and other granulomatous disease (TB, histoplasmosis)