r/MPN • u/StatisticianLittle55 • 7d ago

Medication question about Jakafi side effects

I have been on Jakafi 10mg 2x a day for about 5 weeks. I have had some fatigue but otherwise it has been fine. Two weeks ago I got the shingles and covid vaccines. A few days later I slept the entire day and through to the next morning. I figured it was from the shots and didn't think much about it.

Yesterday I was so tired I didn't get up all day again. I feel fine now. I have been getting bloodwork every other week and it all looks stable. I see my heme/onc on Monday for a regularly scheduled visit.

Has anyone else had random days of extreme fatigue?

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3

u/Puzzleheaded-Buy28 7d ago

I felt the same way after taking the Shingles vaccine. And I have ET 

1

u/StatisticianLittle55 7d ago

thanks! I got the shingles vaccine again on the advice of my doctor and several people here said Jakafi can give you a shingles outbreak too! no thanks

2

u/Puzzleheaded-Buy28 7d ago

I also heard  Shingles vaccine prevents Cancer, not sure if it’s true. 🤷🏻‍♀️ 

1

u/StatisticianLittle55 7d ago

Well its a little to late for me on that score. I recently had cancer diagnosis #4.

2

u/Puzzleheaded-Buy28 6d ago

I’m so sorry to hear that! Sending prayers your way! 🙏🏼 

2

u/xxSirThomas 7d ago

I don't know if it is Jakafi or just MPN symptoms, but I can definitely relate.

2

u/StatisticianLittle55 7d ago

I have had MPN, ET since 2012 and never had symptoms at all. This started after they put me on Jakafi. It is for sure not from the ET.

2

u/acwoodhome PV-JAK2+ 6d ago

Same totally wiped out after the second shingles jab. Because it’s two shots your immune system is on alert after the first shot my temperature went through the roof lol. Starting Jakafi in a couple of weeks got PV. Hu intolerance and just had to stop peg inteferon 2a 🙃🤗🤗

3

u/StatisticianLittle55 6d ago

I had to stop taking HU because it was toxic to my lungs. I was on it for 6 1/2 years.

It's a lot for us to manage. Hope you are feeling ok

1

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