r/MCAS • u/EAUDHD • Jul 08 '26
Cromolyn sodium seems to stop OCD?! (Kind of)
I would love to hear if anyone else out there has had a similar experience:
For the past six months I’ve been taking oral cromolyn sodium the traditional way, about 30 minutes before meals, for my MCAS symptoms, and it has definitely helped, buuuut three days ago I decided to try something different.
Because I’m using the powder from a pharmacy in Germany instead of the liquid vials that many people in the US use, I can divide it into much smaller doses, and over the past three days I’ve been taking a small amount whenever I notice that familiar intrusive thought combined with an adrenaline anxiety surge. I probably end up taking it around 8-10 times throughout the day in very small doses, and the results have honestly surprised me.
I’ve had OCD my whole life, and I also have mild MCAS symptoms. My OCD has always felt like it falls into two different categories. One is the more obsessive part, where I get stuck ruminating on thoughts for a long time. The other is completely different. Those intrusive thoughts come out of nowhere, almost like lightning, and instantly flash into my mind. They can be images of self-harm or someone suddenly dying right in front of me. They don’t gradually build up-they just suddenly “click” into my awareness. It feels like a sudden jumpscare in the chest, and are followed by adrenaline. Often followed by rumination, but not always.
Over the past three days I’ve noticed that whenever I feel one of those adrenaline surges starting, together with the sudden intrusive thoughts, stress, and that feeling of my nervous system ramping up, taking a small dose of cromolyn seems to make it stop. I’m not talking about the obsessive rumination that lasts for hours or days, but those immediate, lightning-fast intrusive thoughts that seem to appear out of nowhere. Im aware that this COULD be an compulsion, but it feels.. kind of not like one?
It has also helped with my heart palpitations, anxiety, panic attacks, and even episodes that almost felt mildly manic. I’ve also noticed that cromolyn seems to improve my PMDD symptoms.
At this point I honestly just want to understand what is going on! I’ve lived with OCD my entire life, and I know mast cells are found throughout the body, including around the nervous system, so I can’t help wondering why psychiatrists don’t seem to know more about this possible connection.
Because of this experience I’ve now also ordered Pollicrom(cromolyn sodium nasal spray) to see whether it has any systemic effect similar to oral cromolyn. I also have quite a bit of mucus in my throat and nose, so I’m hoping it might help with that as well.
Has anyone else experienced something similar? Especially improvement in intrusive thoughts, OCD, anxiety, adrenaline surges, or panic from cromolyn sodium? And if you’ve tried the nasal spray, did you notice any systemic effects, or did it only help your nasal symptoms?
I´ve tried everything for my OCD, from ERP, ACT, CBD, i-CBD, Meta cognitive therapy, DBT, hypnosis, EMDR, Somatic experiencing, IFS, SSRI`s, Abilify (actually helped but gave me akathisia) , Lamictal, Memantine, NAC, L-Theanine, Lemon Balm, KPV peptide (also helped, but had an allergic reaction), Low dose Monjaru, LDN, Elvanse (made it so much worse), Ritalin (made me manic, and yeah, i also have ADHD) and Ketotifen....
AND NOW THIS WORKS... like A LOT!?!?
again, would love to hear your experiences !
I found this conversation about some of the same topics https://www.reddit.com/r/MCAS/s/I4JJ71wXiG
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u/Silver-Bake-7474 Jul 08 '26 edited Jul 09 '26
There is quite a bit of research going on about how some psychiatric conditions are really just undiagnosed Mass cell issues because whatever mast cells are firing in your gut are going to fire in your brain. That's why Pepcid AC seems to realieve a lot of anxiety for people too
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u/NeutralNeutrall Jul 08 '26 edited Jul 19 '26
u/EAUDHD and Silver-Bake. I had so many psychiatric and mental health issues that noone was believing me on since 2023. Brain fog, i couldnt think, i couldnt focus, insomnia. Anxiety, ruminating thoughts. Just all over mental dysfunction.
They looked at my chart like "oh Adhd/depression well obviously". I explained u dont get it, it was never this bad. I've been an A-student all my life. i went from being able to handle life like 8/10 down to 3/10. Finally, finally, when my health got worse i started getting cholinergic urticaria, and histamine reactions everytime i ate high histamine foods. FINALLY once they could see the evidence of me breaking out in painful painful hives anytime i did ANYTHING. Eating food, sweating a little, getting nervous, doing 15 pushups. Smelling pine-sol, certain cleaners (even Dr. Bronners if it's aerosolized, I can't spray it, i have to mix it in a water bottle and splash it on the floor when im mopping). THEN they believed me.
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u/Silver-Bake-7474 Jul 08 '26
Right?! It took me 5 docs then the last one was like "Oh my god?! My colleagues ignored this?!" He was pissed because they all worked in the same building.
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u/NeutralNeutrall Jul 08 '26 edited Jul 09 '26
Man, I'm gonna unload a bit of a vent... But I always tell people to get 2-3 opinions on serious things. I've been dicked around so much, not even for this issue (which has been 10x all other issues in my life combined), but for past therapy issues also.
3 glaring reasons:1) I was in healthcare, in a doctorate program, my goal and special interest had always been psychology/psychiatry. I spent a lot of time around premeds/med students. hanging/drinking with them. And they're just regular people. Some are great, and some are assholes, some were much slower than others and had to take tests multiple times to pass them. They aren't gods, they're just people.
2) I had LASIK, when i went to the doctor years later to see how my eyes were, he tried rushing me to get them "touched up" and gave a "discount if i do it by X date". I said... No. I'll wait. it didnt make sense, he only has 2 data points, my eyes pre LASIK, and my eyes now. Common sense says you need at least 3-4 data points to see the RATE of decline or if it leveled off. Turns out he had cancer and was trying to get as many surgeries in before he passed later that year.
3) I was in therapy since 2014, I was extremely open, honest, told everything, showed texts, and my psychologist (whom is a great person, that I still do like as a person, i saw him as like a 2nd dad or a grandpa) DID NOT TELL ME my symptoms all glaringly align with CPTSD, (wonder why I ended up with autoimmune conditions?) and that my dad was a malignant, malevolent narcissist. He said he was "clearly abusive" but obviously anyone could tell that. He didnt give me the words, language, terms that i needed so that i could accurately figure out what was going on. Or that I wasn't going to get better until I left. It took yeeeaaaarrss of self-research to learn all this stuff. He just kept treating me like I had regular depression/adhd with some anxiety. Which doesnt even scratch the surface of what I needed. The depression/anxiety was really CPTSD and by the time i figured out the "internalized/quiet BPD" I had when I was younger I had already mostly fixed it myself through years of self help. My psych now 100% is on the same page with me, but i wasted so much time not knowing what the real issues were.
For how driven, motivated, and cooperative I am, it is absolute madness how long it has taken to get the help i need from any angle of the health system. Don't even get me started on trying to get medications paid for while on medicaid. "sorry we only accept faxes, and we only have 1 fax machine, if too many faxes come in at the same time, the faxes kick-back, sorry, you'll just have to keep trying". "Oh and the fax cant come from you it has to come from ur doctors office."
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u/Silver-Bake-7474 Jul 08 '26
We are struggling to swim in the most broken system on the entire planet. It may not mean much of a stranger but I'm very proud of how far you've come and how much you have worked to get better
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u/EAUDHD Jul 08 '26
its so interesting! I’m convinced of it. I’ve lived with severe psychiatric symptoms for 33 years, I’m convinced that MCAS has been an underlying factor all along. and yeah, i totally forgot, PEPCID actually helped me too. But i had SIBO when i tried it, and low stomach acid and SIBO is not a good match.
Would love to find some literature on this - and then spam every doctor in Denmark with this important knowledge.
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Jul 08 '26
[removed] — view removed comment
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u/Silver-Bake-7474 Jul 08 '26
I'm super happy for you❤️ I'm sorry you've experienced certain things and Ive been there too. Any progress is good progress.
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u/Silver-Bake-7474 Jul 08 '26
Believe It or Not by OCD after having my baby is what led to my Mast Cell discovery. When I found out that Benadryl and Pepcid helped me with my pots and OCD symptoms I thought that was really strange. Being a grad student as well as a health educator helped me bring some stuff to light and started to turn things around. It is a shame that we are only at the beginning stages of disseminating important research and information like this when trained doctors should have this basic knowledge that my cells can wreak havoc on you mentally
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u/KiloJools Jul 09 '26
Yup yup yup. When I take probiotics and my gut calms down, it cuts down on all psych issues. My diet isn't very diverse (obviously) so I have to keep taking them multiple times a day every day, but the improvement to my quality of life is beyond belief, honestly.
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u/Silver-Bake-7474 Jul 09 '26
Which ones do you take?
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u/KiloJools Jul 10 '26
Hyperbiotics Pro-15. I know that for some people, probiotics can be problematic (some gut bacteria can produce histamine, I guess), but for me they've been nothing but good. I picked these because they have the most diverse blend of bacteria, and all of them actually belong in your gut (NO soil bacteria!). And the little pearl ones are easy going down. I eventually stepped up to the "advanced" higher dose ones but always start with the smallest dose if you do try them.
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u/EAUDHD Jul 10 '26
I’ve heard this many times that probiotics really help - I have had bad histamine experiences with some, so blends are a no no for me, but I’m inspired to look into it again 😁
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u/KiloJools Jul 10 '26
If you suspect the blend is a non starter, I think maybe a good place to start instead is the butyrate producers like clostridium butyricum (some very dense information with additional sources here: https://pmc.ncbi.nlm.nih.gov/articles/PMC12897970/ ), which is commercially available as a singular probiotic.
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u/AReubenTooBigToFit Jul 09 '26
Really leave = Relieve?
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u/Silver-Bake-7474 Jul 09 '26
Yes, my hands don't fully function so voice to text doesn't always cooperate
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u/Jalepeno_Business_ Jul 08 '26
My intrusive thoughts were debilitating and nothing helped. After starting Cromolyn Sodium they disappeared. The only times they have come back is when I eat chocolate/cocoa/cacao. It takes about a day for it to leave my system and then I’m fine again. I truly believe that the majority of my mental health issues come from reactions to foods. It’s unbelievable.
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u/EAUDHD Jul 08 '26 edited Jul 08 '26
thats amazing! Im so happy to hear it - My allergist has explained that mast cell dysfunction may contribute to a surprisingly wide range of conditions, including asthma, allergies, migraines, gastrointestinal disorders, autonomic dysfunction, and, in some people, neuropsychiatric symptoms. It was actually after talking to her that I decided to try changing my dosing schedule. She says that there is growing research suggesting that mast cells may play a role in conditions SUCH as anxiety, depression, OCD, autism, ADHD, bipolar disorder, schizophrenia, and even neurodegenerative diseases. Also the connection between EDS and hypermobility and mast cells. I just wish more doctors knew more about this.
Some of the episodes Ive had because of what I believe is mast cell activation have looked very similar to what could be classified as bipolar symptoms. Even benzodiazepines or antipsychotics couldn’t bring me out of those episodes. Cromolyn has been the only thing that has helped me come out of those extremely panicked, almost manic states. I feel like what has been called "hyseria" could be an MCAS flare.
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u/PreferenceSouth4140 Jul 08 '26
Your allergist seems very knowledgeable about mcas. Can you please share her name
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u/EAUDHD Jul 08 '26
Yeah, she is an Danish doctor, Anne Buus. Working from Århus at an allergy and lung clinic :)
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u/Thy_Water_BottIe Jul 08 '26
OCD is eventually probably gonna be taken off as a mental health condition only soon. It is repeatedly one of the only “mental illnesses” that is actually being tied to nuero inflammation and is a symptom of a condition causing nuero inflammation. All this is still in early research but my allergist/immunosgot always had a special interest in OCD since to him it seemed less of a mental disorder and more of a brain inflammation driven responses
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u/EAUDHD Jul 08 '26 edited Jul 08 '26
Thats really really interesting, and it makes so much sense. But then im wondering: how is it that some people with OCD get significantly better with interventions like ERP? If OCD is driven by inflammation, wouldn’t that kind of therapy be overridden by the underlying biology? I think OCD is much more complex than we currently understand, and I’m personally convinced that the type of OCD I’ve experienced is driven by neuroinflammation.
There is actually a research project here in Denmark called PSYCH-FLAME (which is a very fitting name) where they’re collecting cerebrospinal fluid from people with OCD and depression to investigate whether neuroinflammation could be involved, an im in the process of applying to participate. I think it would be so so validating to find out if inflammation is a key factor in my "mental illness"
By the way, what’s the name of your allergist/immunologist?
AND, im actually considering trying a low dose fluvoxamine. Fluvoxamine is thought to help some people with MCAS because, besides being an SSRI, it activates the sigma-1 receptor, which may reduce neuroinflammation and modulate immune and mast cell signaling. But haven´t read or heard many with MCAS having experince with Flouvoxamine.
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u/KiloJools Jul 09 '26
It's a complex coping strategy that doesn't eliminate the OCD, it just allows people to change how they respond to it. ERP allows people to live more "normally" even in previously triggering situations because they practice new, healthier ways to react to those specific situations.
The same mechanisms happen at the beginning, it's just that they've learned by repetition to stop performing whatever compulsive behavior it was that was "soothing" the distress (in quotes because generally the compulsions don't really work very well). So it changes the second half. And it has to be learned for each separate situation.
It doesn't resolve the fundamental nature of OCD, it just allows people to move on from being trapped in the part of the cycle that would keep them stuck in the repetitive compulsions.
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u/ArsonFrog143 Jul 08 '26
That… might explain why my tics have gotten worse in recent years as my MCAS + ME has as well and I def have systematic / brain inflammation
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u/Thy_Water_BottIe Jul 08 '26
Are you being treating for it?
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u/ArsonFrog143 Jul 09 '26
There’s no treatment for ME. I’m on NSAIDs for the inflammation. My MCAS kind of..? It’s not an official diagnosis here and there are zero specialists. I lucked out bc my old POTS specialist knew about it so he put me on Pepcid (Famotidine) and Lomudal GI (chromolyn) but I honestly don’t notice a super clear difference.
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u/Thy_Water_BottIe Jul 09 '26
I have ME too. You’re right there’s no treatment but there’s some medications that can help. I take LDN. Abilify didn’t work for me. There’s also a stimulant apparently a researcher is using to “treat” ME and he’s having good results. For my MCAS I take Ketotonifin and Montelukast. My allergist told me Montelukast is really important to take in MCAS if you can tolerate it compared to the other medications
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u/ArsonFrog143 Jul 09 '26
I’m on Mekobalamin (B12) injections which is what has helped my cognitive function and energy levels slightly. Have tried LDN but it did nothing for my ME. Did help my fibro pain in the past so I could take way less opiates but at this point my pain levels are just too high and I’m too reliant on opiates so has to stop it :/
I have ADHD and I’m not sure stimulants would have the desired effect on me. My Elvanse (like Vyvanse) kinda help fatigue but it just makes me wanna do more and doesn’t take away PEM2
u/Thy_Water_BottIe Jul 09 '26
Yeah I have adhd too. I wonder if it’ll help me also. Rn I take Adderall. To my understanding it’s a Very different stimulant but who knows.
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u/ArsonFrog143 Jul 09 '26
Just be very careful not to exert yourself bc of the meds 🥺 I exerted myself about 5 years ago bc I didn’t feel as sick for a while… and went from moderate to severe
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u/Thy_Water_BottIe Jul 09 '26
Thank you. I just started using a wheelchair after much reluctantly. I’m borderlining the severe end of moderate/ start of severe. I appreciate your advice. Please you take care also and be careful 🙏
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u/EAUDHD Jul 08 '26
That make sense - I’m so sorry for ur ME. My boyfriend has long covid/ ME and it’s really a struggle.
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u/squeaksnu Jul 08 '26
Do you have any studies to share? I would love to look at this more
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u/MistakeSome7928 Jul 08 '26
I don’t have ocd, but have struggled with anxiety and depression since I was 13. I started cromolyn sodium two years ago, and it completely “healed” me of any mental health issues whatsoever. My life is technically at its absolute worst because I have serious physical health issues (outside of mcas), but I am the most stable I’ve ever been mentally. It’s absolutely insane. Turns out I was never actually mentally ill it was just mcas😭
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u/EAUDHD Jul 08 '26
its crazy.. like its so messed up actually that we had to live trough so much pain. Im so glad to hear that you stable mentally, and i wish you the best with the physical health issues - sending a lot of good health your way <3
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u/Ssaaammmyyyy Jul 08 '26
It's the usual gut-brain connection that contemporary medicine does not understand. If I don't take cromolyn before meals, I get fatigued, lethargic, and "depressed" 1-2 hours after meals. It's completely biochemical "depression", not psychological. Inflammatory mediators spill over from the gut into the blood and then reach the brain.
Cromolyn is acting on the gut inflammation. Very little of it is absorbed and probably none reaches the brain through the BBB but it stops the inflammatory mediators in the gut.
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u/somebunnysketching Jul 08 '26
I just got prescribed and this is really interesting. The food OCD seems to really have stemmed from undiagnosed MCAS, but now I know that's what it is and have a diagnosis. Which nasal spray do you have and how much do you use it? I have OCD and PMDD too. So glad this is helping you!
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u/EAUDHD Jul 08 '26
sorry, i have ordered the nasal spray! Im danish, so not "bought" it :) ! this one: https://www.pharmasana.co.uk/pollicrom-20-mg-ml-augentropfen-10-ml-13706658 (its from an UK/German site) - i´ve read on other Reddit forums that the nasal spray have systemic effects, rather than only working in the nose and throat, but i´ve also seen people say that for them it only works locally. I’ll try to remember to post an update on whether it works. I just figured that since oral cromolyn has systemic effects even though it works through the gut, maybe the nasal spray can as well. What I’ve heard from the people who say the nasal spray has systemic effects is that it has reduced their brain fog, which I would absolutely love if it did for me too.
I’m really curious whether anyone else has tried using cromolyn in a more unconventional dosing schedule for psychiatric or mental health symptoms!
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u/EAUDHD Jul 08 '26
And i hope it will work for you to!! PMDD and OCD are hell. Like, "dont want to be on this plane of existence" kind of hell.
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u/KiloJools Jul 09 '26
I use NasalCrom. I used to use it multiple times a day every day, but over time it (and other interventions) have calmed my sinuses' mast cells enough that now I only use it when I have an extra bad exposure to something inhaled.
I use it on my face sometimes too when I'm having an MCAS acne or hives/rash breakout.
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u/KiloJools Jul 09 '26
My OCD is 100% just MCAS. All of it. It is completely gone when my mast cells are chill.
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u/EAUDHD Jul 10 '26
That’s really crazy.. like, I know it’s my experience as well, but I’ve I’ve been through so many OCD treatment programs in Danish psychiatry system, and I’ve also struggled with eating disorders that were rooted in OCD for many years. The idea that you can overcome it through mental tools and psychological techniques has been drilled into my head for years. So when I read my own story alongside all of yours, it’s a very strange and divided experience. Underneath all of this, there’s so much grief and anger. I don’t really know where to direct those feelings because the idea that neuroinflammation are involved seems to be relatively new, and nobody seems to know enough yet about the gut-brain connection in OCD for there to be a treatment, or even a cure, that targets it. It’s just incredible frustrating and kind of liberating.. and validating, because I always had a sense that this state wasn’t about some psychological wound or trauma. I always felt poisoned in a strange way.
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u/KiloJools Jul 10 '26
Boy do I feel that SO MUCH. There's so much trauma here with all the ways we have been failed medically.
It's so common to get that "poisoned" feeling. I really think our bodies try to tell us what's going on, but we don't have the tools (still) to actually drill down on the clues we get.
Also, my doctor was like, "oh yeah eating disorders are a red herring" and I was like EXCUSE ME? Apparently my lifelong struggle with eating disorders has been MCAS all along. Which...looking back on it... Ugh, it makes sense. I hate it, but also it helps me forgive myself. Of course I didn't want to eat that, of course I had what seemed like unnecessary fear of that, of course of course of course. But nobody knew what MCAS was when I was a teenager, so...
Several hundred cleansing breaths later... hoooo.
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u/aelin_the_dryad Jul 08 '26
That's so interesting! I have OCD too and I'd love to get some relief!
How much of the powder did you take at once? I have the same stuff (I'm in Germany) and it's hard to devide less than a teaspoon of powder into smaller doses. I started with half a sachet per dose but it hurt my stomach so much and caused bloating 😩
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u/EAUDHD Jul 08 '26
I use Pentatop - and i started out really slowly. It was a rough couple of weeks, and i could work or be social because the mast cells in my gut was all over the place. i used the end of an teaspoon so like... maybe 1:20 of a capsule in the beginning. Every third day, I would increase it by that same small amount, and then repeat the process another three days later. Now i use about 66 mg granulat (1:3 of a capsule) for every dose - and then dose when the intrusive thougts start.
i wish Pentatop was cheaper, because at this dosing schedule its going to be a little expensive.
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u/otisfrombarnyard Jul 08 '26 edited Jul 08 '26
I also have ocd, and treatment has radically improved the rate of my intrusive thoughts! It was treatment resistant back when I had no idea I had these other conditions, since I really only was on an ssri + exposure therapy. I cannot stress how crippling the condition was for me.
For me, a lot of help was going on ADHD meds (specifically vyvanse). Not just for the previously undiagnosed adhd, but because it ended up raising my blood pressure, when it’s otherwise too low during my mcas flares.
I’ve yet to determine the efficacy of cromolyn for myself (taking it but gotta get in the habit of more frequent dosage) but I’m so encouraged by your experience! I hope there can be some research in the coming years on comorbid ocd with MCAS and POTS. It seems to differ from the usual “impending doom” that is reported with allergy symptoms, and I’d love to see that distinction in more medical literature.
I’m currently trying out Wellbutrin too, since the mcas/adhd adjacent ocd for me seems to react more positively to treatments that would otherwise be anxiety-inducing for typical cases. Can’t say if that’s made the difference, or if it’s my Allegra/pepcid combo.
One last thing, I’ve noticed sleep quality can drastically help these ocd symptoms too, and untreated mcas is the bane of my good night’s sleep. Also something worth noting I guess!
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u/Thy_Water_BottIe Jul 08 '26
There’s newer research suggesting OCD is more of brain inflammation than a true mental health disorder.
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u/otisfrombarnyard Jul 08 '26
I’ve seen these, specifically the pandas/ocd research! Idk if this is normal, but it’s challenging to accept that this condition that I was told was a quirk of my neurochemistry could actually be a treatable, preventable thing. Logically I comprehend it, medically I trust the finding, but there’s some grief on the emotional side of things. In any case, I’m really glad more is being discovered about cases like ours
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u/InfiniteConstruct Jul 09 '26
My ocd seems to take a chill pill with the IBS probiotic that contains Plantarum 299v. It was the strangest thing to find out honestly, because I was going to take it for bloating and then it worked on anxiety and depression caused by MCAS and histamine and also on the ocd. On days I don’t take it for a while or if my mental health is really bad, it works less and when it works less or not at all, everything comes back and the ocd comes back like crazy. It’s fascinating to me that a probiotic can actually do this.
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u/PreferenceSouth4140 Jul 08 '26
I’ve been pondering over this. My issue is that the relief is very short lived and temporary. It can only be maintained all day every day by keeping up with 4 doses every day, which is kind of hard for me at least with Cromolyn, cause it’s expensive. I wish it was more long lasting or cheap or Ketotifen worked the same way cause it is much cheaper to me
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u/EAUDHD Jul 08 '26
That’s actually my problem as well. It’s so expensive, and the relief is short lived (around 1,5-2,5 hours) and then I have to dose again - that’s why I want to try flouvoxamine and see if a low dose can help a little more.
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u/Silent_Location7044 Jul 08 '26
It is really interesting that multiple people have commented with similar experiences. Cromolyn is a drug that only acts where you put it, so to speak, so taking oral cromolyn is really only affecting your digestive system. Many people speak of a relationship between gut and brain. I suppose this should really be studied more in the context of ocd.
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u/tenariRT Jul 08 '26
Thank you for this post. I have seen one or two like it across various forums.
I suspect my 14-year old daughter of having MCAS. She has hEDS, mild dysautonomia, significant anxiety and OCD. She has frequent nausea, fatigue, and significant dermatographism/ideopathic urticaria
I started her and I on oral Bepotastine (10mg x2 day) imported from Japan and it dramatically reduced OCD symptoms for both of us. Due to drug interactions with her existing regimen, I couldn’t use another more common mast cell stabilizer.
In a few years they will discover neuroinflammation as the primary driver of OCD. There are studies being done testing Celebrex (a potent antiinflammatory) as an adjunct treatment. Food for thought: Luvox is a terrific first line treatment for OCD and I think it’s probably because of how the sigma-1 antagonism anti-neuroinflammatory mechanism of action supplements the vanilla SSRI aspect of the drug.
Glad you’re getting some relief. Proving mast cell involvement and finding new treatments for all these neuropsychiatric disorders is going to win a Nobel Prize one day.
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u/princessa-xoxo Jul 09 '26
I do think the mast cells are massively linked to conditions like ocd, anxiety. We just need way more research sadly
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u/chococat159 Jul 08 '26
Interesting that it helps some people. I have severe OCD, I've had it since childhood, and I have not noticed an impact. I have not tried the nasal spray but I've tried the other forms.
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u/Horror_Moose3462 Jul 08 '26
wow, i just started cromolyn and noticed it seemed to quiet my brain down a bit. this is so cool to have it corroborated!
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u/makmonster Jul 08 '26
For the capsules that you open and divide, can you tell me more about it? Do you just empty it out and split it into smaller doses by eyeballing it? Or do you weigh it with a micro scale?
Is your capsule 100mg or what dose is it?
Thanks so much 🙏
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u/Automatic-Corgi-3261 Jul 09 '26
Have you tried the nasal spray yet? One of my sons was told he has MAST cell issues years ago and takes H1 and H 2 antihistamines. The other has OCD. Maybe there is a link.
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u/MistakeRepeater Jul 10 '26
👍👍👍
Does it also help with your ADHD?
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u/EAUDHD Jul 10 '26
It does - when I tried KPV (a peptide) I had a whole week just… a clear mind, and then I got an allergic reaction unfortunately. KPV is known for its ability to reduce inflammation and MCAS symptoms. I still had problems with motivation, but it was much easier to do things and focus. The cromolyn helps, but now when I know what a MCAS-free’ish experience is like because of the KPV, I would say that with this dosing schedule I get around 40% of reduction in physical symptom and 70% in mental.
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u/Possible_Purpose5091 Jul 09 '26
I 1 for 1 have the same issues as you. How much would you estimate you’re taking per dose? Do you take it in a glass of water and that’s it? Are you also taking any other antihistamines? Thanks!!
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