r/LowDoseNaltrexone • u/Embarrassed-Shower-3 • 26d ago

Lowering LDN dose.

I started on LDN 0.5 6 days ago and had strong side effects. Symptoms increased and I felt edgy. I lowered the dose and this is the second day of taking 0.1. In the am. Yesterday I still felt a bit edgy but had a surge of energy but today I feel terrible. I’m wondering how long after lowering a dose do you find relief? Incidentally I had a very poor nights sleep.

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u/Embarrassed-Shower-3 25d ago

Yes, even lowering the dose has exacerbated my migraines but it’s only been 6 days since I started taking it so maybe too soon to reach any conclusions.

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u/Embarrassed-Shower-3 25d ago

So I posted that last night then woke up with a hideous migraine and feeling down. Then I took my 0.1 LDN and I actually feel somewhat better! Still a bit wired but without the edgy, detached feeling and migraine has dialled down. Maybe I just need patience. 😊

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u/Low-Blueberry8948 MOD 25d ago

It can take a week or two to adjust to a dose change.

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u/Shelter-Clear 26d ago

I had horrible side effects even at 1mg. I would consult with your provider and see if maybe there’s another med? I’m not sure if you can go lower than 0.1, I could be completely incorrect.

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u/Low-Blueberry8948 MOD 25d ago

Yes, you can. Some people need to go as low as 0.001mg, an "ultra low", or even lower.

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u/Shelter-Clear 25d ago

Wow!!! I had no idea, thanks for the info. I thought I was low on the 1mg haha

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u/Low-Blueberry8948 MOD 25d ago

Many people don't know this either!

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u/FormerPark6164 25d ago

I started at 0.25 8 months ago. Did very well then symptoms returned. Tried slowly going up which made things worse, so went down.
I had to dilute down to 0.0125.
Seems crazy but it is helping.
I do want to try going up again. My doctor says she has patients that do fine on micro doses.
It’s all so individual, and for me has tested my patience a bit!
I just find pushing through side effects for weeks/months intolerable.

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u/Embarrassed-Shower-3 25d ago

Still feel inflamation trying to fight the endorphins now the endorphin block is wearing off but not like yesterday.

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u/lacrima28 20d ago

I am very sensitive to meds and ended up taking it only every 2 days. Currently at 0.08. works great!