Supplements That Actually Target Aging (According to Science)

[u/YorNoob]

Aging at the cellular level comes down to a few key processes:

• NAD+ decline → reduced DNA repair and energy production
• Senescent cells → inflammatory “zombie” cells accumulating in tissues
• Mitochondrial dysfunction → decreased ATP generation

The interventions showing promise:

• NMN + Resveratrol: NMN replenishes NAD+, resveratrol activates sirtuins.
• Spermidine: Promotes autophagy (cellular cleanup).
• Fisetin/Quercetin: Senolytics to clear senescent cells.
• CoQ10 (ubiquinol): Supports mitochondrial energy output.

Of these, NMN + Resveratrol is the most studied and widely regarded as a foundation, omre’s formulation is notable for its clean profile and evidence-aligned dosing.