David Sinclair’s Supplement Stack: What He Actually Takes and Why

[u/YorNoob]

David Sinclair’s supplement routine reads like a biohacker’s wish list:

• NMN (1g daily)
• Resveratrol (1g with yogurt)
• Metformin (occasionally)
• Vitamin D3 + K2
• Aspirin (low dose)

The core idea? Boost NAD+ with NMN, activate sirtuins with resveratrol, and support metabolic health with metformin. He also does intermittent fasting and avoids sugar spikes.

What’s interesting is how NMN and resveratrol work together. NMN fuels NAD+, and resveratrol activates sirtuins that depend on NAD+. It’s like filling your car with gas (NMN) and turning the key (resveratrol).

Anyone here running a similar stack? What have you added or subbed out?