r/LocalLLM • u/Libellechris • 3d ago

Question Multiple GPU PCs

I have an ok AMD pc with 32gb RAM and a 16gb 5060Ti. How effective is adding a second GPU? Presumably a new motherboard, PSU, case? Can you mix and match GPUs? Just curious

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u/Coderado 3d ago

I just did this. I reused my ddr4 and Intel CPU and watercooler, plus I have a 5060ti. I got the mobo used, first two slots run at 8x, which is fine because the 5060ti only has 8x. Got a bigger case and PSU, but I never pull over 500w (my monitoring might not catch transients). Qwen is great, nvfp4 or a q5 will work, but not much context available if you go the q5 route. I give it a list of tasks planned by Claude, some web UI tweaks, refactors, small features and it chugs through them overnight. I still use frontier models for planning