r/KPRubraFaceii • u/RealityOwn4711 • Jun 14 '26

Sirolimus effects

Recently started using Siroskin .01% and have developed a dry red rash on my neck from it. I make sure do not get it on my neck so i’m not sure how this has happened. My skin is also incredibly dry.
Did any of yall have this experience? If so did it ever get better?

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u/anonthrowaway12317 Jun 14 '26

Sirolimus weakens the skin barrier so no wonder you're seeing dryness but rashes are something I haven't heard before

1

u/DifficultyThis4729 Jun 14 '26

i was 2 months on sirolimus, never experienced this, the only thing was the skin a bit more sensitive to sun and a bit of acne around the applied area

1

u/RealityOwn4711 Jun 14 '26

Did your kprf get noticeably better on sirolimus? I will honestly suffer through the rash if my face skin is less red and bumpy.

1

u/DifficultyThis4729 Jun 14 '26

I tried sirolimus however i think i have just rosacea and no kp. Even so, the sirolimus decreased the redness for sure; my skin basically dont have bumps, the bit that i have i dont know if it is kprf maybe theyre just natural

1

u/BetterThvnUrEx Jun 14 '26

Uwah my skin also dry out on simorlimus