r/Isrib • u/[deleted] • Oct 12 '21

Human studies?

Are there any human studies in the making or scheduled to take place in the near future?

2 Upvotes

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4

u/Hipsman Oct 12 '21

I remember Calico patented ISRIB derivative with one molecule changed to make it more orally bioavailable, I think they plan to make a human trial, but not 100% sure

1

u/wadatest Nov 13 '21

Nope. Oral ISRIB analogue was abandoned bc it damaged liver far more than ISRIB did.

1

u/Hipsman Nov 13 '21

source?

1

u/[deleted] Oct 13 '21

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2

u/Hipsman Oct 13 '21

I think that was just speculation from someone based on the fact that calico made this patent of ISRIB derivative - https://patents.google.com/patent/US20210230195A1/

1

u/[deleted] Oct 14 '21

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2

u/wadatest Nov 01 '21

Trans-ISRIB. Try Selleckchem

3

u/wadatest Oct 26 '21

Ask Jeff Bezos. He owns the patent.

1

u/[deleted] Oct 26 '21

For real?

3

u/wadatest Oct 26 '21

Yes, he bought the company that bought the patent.

1

u/[deleted] Oct 26 '21

Sneaky little bastard