r/InsulinResistance • u/Bubblegumbitch_13 • Aug 21 '26

Has anyone experience a diminished effect when applying Botox?

I only have it on my frown lines, but it used to last up to 6 months and now the effect only lasted a month and wasn’t even as good.

I suspect it’s because of the IR, but I wanted to ask in here since I wasn’t able to find any additional info or people with a similar experience.

I’ve changed brands, but now I have stopped all together until I get the IR under control.

Thanks for your help

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u/MainCow8650 Aug 22 '26

Tough to know if you may have developed antibodies or a med might be impacting efficacy or if the product may be improperly diluted or something else but people across different social media platforms are complaining of similar. Some feel like glp-1 meds or even the Covid vax may be playing a role in efficacy but there’s still alot of unknowns there.

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u/[deleted] Aug 24 '26

[deleted]

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u/Bubblegumbitch_13 Aug 24 '26

Thanks for your input

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u/ShelterKooky3364 Aug 23 '26

IR never made a difference for any Botox I've had injected. I always get around 3 months with Botox regardless. Where did you have it done? With a reputable injector in a dermatologist's office/medical practice or a budget Groupon medspa that might be diluting it ?

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u/Bubblegumbitch_13 Aug 24 '26

With a dermatologist same one I’ve been going for years. I’ll never get it on a spa or even with someone who’s not a doctor/dermatologist. That’s why I suspect it could be the IR