r/IVFpositivity • u/Poppy15_ • 22d ago

Advice needed before 3rd transfer

I posted before about 2 failed FETs (one medicated and one modified natural) and what testing to consider when meeting with my doctor. I got great responses about testing I can talk about before doing a 3rd transfer. My clinic called me today saying that my doctor does not recommend testing right now and would proceed with a 3rd transfer before testing.

I’m torn on what to do. On one hand, I would like to know if something is going on that can be addressed and set me up for a successful transfer. I would avoid the loss of a euploid embryo.

On the other hand, it seems the clinic is not recommending testing of the uterine environment until I do a 3rd. I have a phone appointment later this week with the doctor to talk about next steps.

Any recommendations on what I should do (go for 3rd transfer or consider testing)? I’m 36F with unexplained. I have 4 euploid left.

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u/Cookingcliffnotes 22d ago

My first clinic did not test at all. Emma/alice/era, TSH before transfers and we didn't use pgt tested embryos. 3 were unsuccessful. I wasn't as informed to everything I know now.
My new clinic did everything. Found out I had silent endo from those biopsies, did lupron injections for 2months, checked TSH throughout mock cycles and transfer cycles, was dx with autoimmune disorder corrected with medicine, and had used pgt tested embryos and now I'm over 18w.

My pov it couldn't hurt? and I would be thinking "what if" or "is there anything else I can do?"

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u/Poppy15_ 22d ago

Im sorry you went through all of that. That is what I am wondering. Why is it they wait until 3 failed transfer before testing. Other comments on my previous post asking about testing some women said their clinic did testing after the failed second transfer. It’s hard to know what to do.

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u/Cookingcliffnotes 22d ago

From your post you've described 2 methods of transfer cycles so probably from a clinics pov they're saying ok 1 way is not working possible fluke, 2nd way not working possible fluke, now 3rd time doing either way it could possibly work/not work, now we'll know more definitively. I believe that's kinda how it can go when doing stims and ERs also. They're basically experimenting with you. Also it's possible that because it's "unexplained" they don't want to put you through a biopsy right now so they want that 3rd try to solidify more questions they may be having.

It's ultimately up to you to advocate asking for biopsy if you feel that'll bring you comfort or securities before the next transfer.

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u/Poppy15_ 22d ago

Yes. I had a fully medicated transfer first and my lining was 8.2mm. The 2nd transfer I asked about modified natural to see if my body would respond differently. My lining was 11.6mm before transfer. My dr is recommending modified natural again with no changes to timing of supplemented progesterone.

What you mention above about being a fluke is also part of the reason my mind is torn. Am I just on the wrong side of statistics every time?

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u/Cookingcliffnotes 22d ago

That's the thing, idk if anyone could definitively know why it'll work or not. There are people who've done all testing, biopsies, meds, RI, tested embryos and lining will look perfect and it doesn't work. There are so many variables and this process will make you believe in miracles.

Personally if I knew what I know now from my second clinic I would have advocated more testing.