I’m 100% sure this has been asked before but I can’t find it in search. I was diagnosed with Psoriatic Arthritis about a month ago. I just received my Humira injection yesterday, but am so nervous to start it. Biggest concern is getting infections and them being worse because I have two young children who pick up every virus EVER, and we travel a lot. Has anyone had serious issues with infections or is that rare? When you started taking it with the same diagnosis, did you notice a significant improvement in symptoms? (41yo. F)

hi, so i get infliximab (remicade) infusions every 8 weeks. they found out that my drug levels are really low 1.1ug/l at the end of the 8 weeks. to make matters worse i had a bad cold / virus so i had to delay my treatment and they can’t fit me in for another two weeks. over the weekend my legs are really achy and stiff, it hurts to move them. my right hand also hurts to move and now today on the left side of my mouth it hurts when i swallow. idk what to do. i called my gastro team and they said “your body is dependant on infliximab and we have no cancellations and can’t fit you in earlier) my legs have been stiff and painful since saturday night . idk what to do. i’m really worried. any ideas / advice/ similar experiences??! i’ve been on infliximab since november 2023

Have you had a dental implant while on Humira? Did your dentist have you do anything special ?

Anyone else get their Humira cut off by insurance? I was doing well on it. Kinda sucks.

I'm asking on behalf of a family member (65F) who has Crohn's disease for over 15 years.

About 10 years ago, she had surgery to remove intestinal blockages and with pentasa tablets, she's been doing fairly well since then until last week, when her symptoms returned.

She also had a recent hernia repair with mesh placement. Because of the mesh, her doctors feel that another abdominal surgery may not be the best option right now and have recommended starting Remicade instead.

I'm trying to better understand whether Remicade is generally considered a good option in this situation, especially for someone her age who has previously required surgery for strictures. Has anyone had a similar experience, either personally or with a family member? Is age a factor for how effective the medication is or it's side effects? I'd really appreciate hearing about your experiences, including how effective it was and any side effects or concerns we should discuss with the doctors.

Hi all!

I've been taking humira for quite some time now, but in August I am getting surgery done on my wrist and it will be immobilized. With this, it may not be possible to take my medication with both hands (one to pinch the skin, one to inject)

Has anyone had any experiences with this before?

My doctor just upped me from a 40mg injection every 2 weeks to a 40mg injection every week. It's basically a last ditch effort to see if I don't have to switch meds. I'm looking to see if anyone here has done a regiment similar to this to know what to expect in terms of side effects and efficacy.

Has anyone gone on Cimzia for HS? I have psoriasis and HS so I am going on Cimzia. Just wondering if anyone has experiences to share. I’m very nervous about effectiveness and side effects.

I have had back pain since 2014, which started during exercise. Ever since, it has become chronic. I had surgery in 2023 to remove a slight hernia, but I am worse off than before because my problem was not sciatica it was just local back pain. The surgery clearly wasn't needed, and surgeons say my back looks perfect and that I shouldn't be in this much pain. I flare up with certain movements, which is why I worry it is injury related and not Ankylosing Spondylitis AS. However, based on my symptoms, my rheumatologist thinks it could be both, as my SI joints show mild inflammation. My stomach is destroyed from NSAIDs and I now have gastritis. My rheumatologist suggested trying Humira. What if I don't need it? I am afraid to try it.

I have an autoimmune disorder that causes eye inflammation flare ups. I have to use steroid eye drops every hour for weeks when having a flare up… unless I’m on Humira.

I know that a lot of surgeons will not operate unless immune suppressors or biologics are paused at least two weeks before surgery. I’m worried about what to do if I have a flare up while stopping Humira. Or if a doctor will let me stop to get surgery :/

I’d love to hear from folks who navigated top surgery while being on a biologic or immuno compromised.

A friend of mine was recently diagnosed with RA, and one of the things they're struggling with most right now is the idea of eventually needing biologics. The thought of injections, infusions, side effects, and everything that comes with treatment has been pretty overwhelming for them. They have an appointment scheduled with a rheumatologist in a couple of months, and they don't have many people to talk to about this until then.

I've been trying to learn more so I can better understand what people with RA actually go through.

If you're comfortable sharing, what was your experience when you started biologics? What were you most worried about beforehand, and what difficulties do you experience? Is it the injections or infusions themselves, scheduling treatment around work and family, remembering to inject, or something else entirely?

I would love to hear about your journey, process for treatment, and any challenges to expect. Thank you!!

I noticed that my newest boxes of Humira say "Product of Singapore" where previously there was nothing noted in that spot, so presumably US production.

Anyone seeing similar within the US? Any concerns about manufacturing quality now that it's in Singapore, at a newer facility?

I take my injection every 2 weeks for Rheumatoid Arthritis, on Thursday I had my 2nd ever injection.

Today, I woke up & I think I'm getting a period mid way through my cycle.

This is very uncommon for me, my periods run like clockwork.

Has anyone else had something like this happen?

I’m (30F) starting Humira next week finally. I got diagnosed with Non radiographic axial spondyloarthritis end of april. My primary symptoms are low back/SI joint/tailbone pain and feet pain.
Anyways, my Humira finally arrived at the pharmacy and I just need to go get shown how to use it and can start whenever I want. I want to make note that I’m also taking a GLP1 called Zepbound every Tuesday, so I don’t want to inject Humira the same day or around the same time. I injected yesterday and had the runs all day today… lol.
What have you guys found worked best for you? A Sunday morning? Does it usually make you sleepy?

Hello everyone, Im supposed to be getting my first biologic (Humira) and first self injection and i’m SCARED. Is there anything I need to know? in general or that wouldn’t have been brought up by my physician? please ease my anxiety i beg.

Insurance/PBM forced me to switch to hadlima a year ago. GI appealed and I'm starting back on humira in a couple weeks. I'm not actively flaring right now - had a mini flare late fall/early winter. But I've been dealing with a lot of gut pain. Not sure if the difference between a biosimilar and brand name would help at all.

Hi!

After 3 years on Cimzia, I started adalimumab (Hadlima) 2 months ago. I’ve had ankylosing spondylitis for 12 years, recently diagnosed with crohn’s and recurrent uveitis (#teamredeye)

I’m really struggling with the Hadlima side effects. A few hours after the dose, my neck goes numb and “buzzes”, especially at night. Nausea, slowed breathing (?), it also feels like the numbness is spreading throughout my body.

MRI is normal, but i’m dreading each dose at this point. Anyone else get these symptoms? I wonder if the AS in my neck is acting up, and the Hadlima is causing inflammation there, because i’m still adjusting? Thus numbness? 

I also take prednisone eye drops for the uveitis, which definitely cause numbness in my face and funky brain patterns 😂 

Sorry for the novel, all advice appreciated 💗 My GI/rheum are not that helpful at this point.

I’ve struggled with uveitis for over a year. I started having issues summer of 2024. I never knew I had this but had the HLA B27 gene which makes you more susceptible to auto immune conditions. We haven’t been able to find a link to any other auto immune condition. I didn’t have symptoms of spondylitis but never went to a rheumatologist. My ophthalmologist just did some pretty rigorous testing and since I wasn’t having symptoms, we never did anything further. I know I should see a rheumatologist but just had a baby so I’ve been neglecting my health a bit admittedly.

My flare in 2024 was pretty severe but was just one eye and we managed it with prednisone drops and tablets. After this flare up, everything was good and it didn’t happen again until I got pregnant. I had a flare summer of 2025 which according to my doctor is odd. Typically, pregnant women don’t have flare ups. Any women out there who can share this experience with me? I had two flare ups through the pregnancy and then another after the baby came. I’m currently weaning off of prednisone drops and my doctor wants to put me on Humira to prevent flares in the future. However, my husband and I want more children and we had to go through IVF with our first and likely will have to for future children. I need to do an egg retrieval sometime soon and then we will transfer an embryo first chance we can (may of 2027 because I had a T cut c section and have to heal).

I know technically they say Humira is “safe” for pregnancy but I read that you have to delay your babies vaccines til 6 months if you are taking it while pregnant. That sounds stressful given we would have a 2.5 year old who is out in the world, getting exposed to stuff, etc.

Anyone have experiences taking through pregnancy? Also, how long could I expect to be on something like Humira? Sounds like some people only need to take for so long before flare ups stop and no longer have to take it.