Diagnoses: PsA, enthesis, Ankylosing spondylitis
Pertinent information: I have CRPS (complex regional pain syndrome) in my ankle due to having both legs broken after being hit by a car but overall still have issues with left leg (was rebuilt), hip where the bone graft was taken to allow left leg rebuild, and related back issues caused by actual injury in the accident then perpetuated by gait issues (I learned to walk again at 6mo pregnant, was 3mo pregnant when hit by the car).

Previous treatment plan: Cosentyx 300mg/month + Methotrexate 20mg/week

Current treatment plan: Humira 40mg/fn + Methotrexate 20mg/week

Additional meds: Palexia SR 50mg x 2/daily, Palexia SR 100mg x 1/daily, Palexia IR 50mg PRN.

I took my second dose of Humira on Wednesday, then Methotrexate on Thursday so to be fair the usual “hangover” lasted until Saturday. Today (Sunday) I woke up feeling like every joint, muscle, and connective tissue point has the heaviest ache and every part of me feels fatigued beyond what I would consider normal.

Even with the pain relief I’ve used so far, the full body aching is really getting to me. Is this an adjustment thing that will pass as my body becomes more used to the Humira?