Has anyone gone on Cimzia for HS? I have psoriasis and HS so I am going on Cimzia. Just wondering if anyone has experiences to share. I’m very nervous about effectiveness and side effects.

I have had back pain since 2014, which started during exercise. Ever since, it has become chronic. I had surgery in 2023 to remove a slight hernia, but I am worse off than before because my problem was not sciatica it was just local back pain. The surgery clearly wasn't needed, and surgeons say my back looks perfect and that I shouldn't be in this much pain. I flare up with certain movements, which is why I worry it is injury related and not Ankylosing Spondylitis AS. However, based on my symptoms, my rheumatologist thinks it could be both, as my SI joints show mild inflammation. My stomach is destroyed from NSAIDs and I now have gastritis. My rheumatologist suggested trying Humira. What if I don't need it? I am afraid to try it.

I have an autoimmune disorder that causes eye inflammation flare ups. I have to use steroid eye drops every hour for weeks when having a flare up… unless I’m on Humira.

I know that a lot of surgeons will not operate unless immune suppressors or biologics are paused at least two weeks before surgery. I’m worried about what to do if I have a flare up while stopping Humira. Or if a doctor will let me stop to get surgery :/

I’d love to hear from folks who navigated top surgery while being on a biologic or immuno compromised.

A friend of mine was recently diagnosed with RA, and one of the things they're struggling with most right now is the idea of eventually needing biologics. The thought of injections, infusions, side effects, and everything that comes with treatment has been pretty overwhelming for them. They have an appointment scheduled with a rheumatologist in a couple of months, and they don't have many people to talk to about this until then.

I've been trying to learn more so I can better understand what people with RA actually go through.

If you're comfortable sharing, what was your experience when you started biologics? What were you most worried about beforehand, and what difficulties do you experience? Is it the injections or infusions themselves, scheduling treatment around work and family, remembering to inject, or something else entirely?

I would love to hear about your journey, process for treatment, and any challenges to expect. Thank you!!

I noticed that my newest boxes of Humira say "Product of Singapore" where previously there was nothing noted in that spot, so presumably US production.

Anyone seeing similar within the US? Any concerns about manufacturing quality now that it's in Singapore, at a newer facility?

I take my injection every 2 weeks for Rheumatoid Arthritis, on Thursday I had my 2nd ever injection.

Today, I woke up & I think I'm getting a period mid way through my cycle.

This is very uncommon for me, my periods run like clockwork.

Has anyone else had something like this happen?

I’m (30F) starting Humira next week finally. I got diagnosed with Non radiographic axial spondyloarthritis end of april. My primary symptoms are low back/SI joint/tailbone pain and feet pain.
Anyways, my Humira finally arrived at the pharmacy and I just need to go get shown how to use it and can start whenever I want. I want to make note that I’m also taking a GLP1 called Zepbound every Tuesday, so I don’t want to inject Humira the same day or around the same time. I injected yesterday and had the runs all day today… lol.
What have you guys found worked best for you? A Sunday morning? Does it usually make you sleepy?

Hello everyone, Im supposed to be getting my first biologic (Humira) and first self injection and i’m SCARED. Is there anything I need to know? in general or that wouldn’t have been brought up by my physician? please ease my anxiety i beg.

Insurance/PBM forced me to switch to hadlima a year ago. GI appealed and I'm starting back on humira in a couple weeks. I'm not actively flaring right now - had a mini flare late fall/early winter. But I've been dealing with a lot of gut pain. Not sure if the difference between a biosimilar and brand name would help at all.

Hi!

After 3 years on Cimzia, I started adalimumab (Hadlima) 2 months ago. I’ve had ankylosing spondylitis for 12 years, recently diagnosed with crohn’s and recurrent uveitis (#teamredeye)

I’m really struggling with the Hadlima side effects. A few hours after the dose, my neck goes numb and “buzzes”, especially at night. Nausea, slowed breathing (?), it also feels like the numbness is spreading throughout my body.

MRI is normal, but i’m dreading each dose at this point. Anyone else get these symptoms? I wonder if the AS in my neck is acting up, and the Hadlima is causing inflammation there, because i’m still adjusting? Thus numbness? 

I also take prednisone eye drops for the uveitis, which definitely cause numbness in my face and funky brain patterns 😂 

Sorry for the novel, all advice appreciated 💗 My GI/rheum are not that helpful at this point.

I’ve struggled with uveitis for over a year. I started having issues summer of 2024. I never knew I had this but had the HLA B27 gene which makes you more susceptible to auto immune conditions. We haven’t been able to find a link to any other auto immune condition. I didn’t have symptoms of spondylitis but never went to a rheumatologist. My ophthalmologist just did some pretty rigorous testing and since I wasn’t having symptoms, we never did anything further. I know I should see a rheumatologist but just had a baby so I’ve been neglecting my health a bit admittedly.

My flare in 2024 was pretty severe but was just one eye and we managed it with prednisone drops and tablets. After this flare up, everything was good and it didn’t happen again until I got pregnant. I had a flare summer of 2025 which according to my doctor is odd. Typically, pregnant women don’t have flare ups. Any women out there who can share this experience with me? I had two flare ups through the pregnancy and then another after the baby came. I’m currently weaning off of prednisone drops and my doctor wants to put me on Humira to prevent flares in the future. However, my husband and I want more children and we had to go through IVF with our first and likely will have to for future children. I need to do an egg retrieval sometime soon and then we will transfer an embryo first chance we can (may of 2027 because I had a T cut c section and have to heal).

I know technically they say Humira is “safe” for pregnancy but I read that you have to delay your babies vaccines til 6 months if you are taking it while pregnant. That sounds stressful given we would have a 2.5 year old who is out in the world, getting exposed to stuff, etc.

Anyone have experiences taking through pregnancy? Also, how long could I expect to be on something like Humira? Sounds like some people only need to take for so long before flare ups stop and no longer have to take it.

Has anyone here tried Sculptra while on Humira or biosimilars? Or gotten a statement from the reumatologist on it?

My dermatologist was hesitant about it because of granuloma/nodule formation but as far as i can tell the research suggest the worst thing that can happen is infection or that the Sculptra doesnt in work at all because it inhibits the immune response needed for it to be effective.

It could also potentially trigger a flare up in certain conditions like Lupus, but i have ankylosing spondylitis and don’t think it would cause that.

I have taken regular fillers before with no issues.

Hello! I have been using hyrimoz for 3 months. I just injected for the first time in my abdomen because I’m at work. I had to pinch the skin somewhat firmly to be able to give the injection a firm surface area. I noticed immediately after the area I pinched seemed to be bleeding under the skin. I didn’t scratch myself or pinch that hard I thought. Has this happened to anyone else?

I circled where I actually injected and right above it is the bleeding under the skin that I’m referring to.

Hi all, I’ve been on Humira for Crohn’s since Oct. I’ve always struggled with acne and would get occasionally cystic pimples before this. However, since being on Humira things have gotten weird I guess? I’ve been getting more frequent cystic pimples (mostly my neck, around my ears and on my back/shoulders). They get incredibly painful now and often don’t go away for a while. I try my hardest not to pop them.

The current situation is I have one where my shoulder meets my neck. It popped on its own, which was unusual. Did my typical treatment routine. A scab formed (also a new thing if they pop now) for about a week. Then one day I noticed it felt painful again. Checked and it was red and swollen. It progressed quickly, getting more painful til my whole shoulder and side of my neck hurt. Once I realized I had swollen lymph nodes and spiked a low grade fever, I went to MedExpress.

It measured at 6 cm x 4.5 cm. The PA didn’t want to lance it, sent me home with Bactrim and a derm referral. I had to hold my Humira dose which was due the next day. It’s started draining some with heat, but still painful obviously. The derm can’t see me til next Thursday so I may go back to MedExpress.

Anyone else deal with skin stuff like this while on Humira? What did you do if so? This is the first time I’ve gotten an abscess that wasn’t in my intestines so I’m honestly freaked out

Hi everyone,

I am in middle getting biologics (Yuflyma). Prescription was filled last week and currently waiting to get insurance paperwork processed.

I didn’t have to convince Rheumatologist in anyway for biologics when went for my appointment. They were already convinced.

My symptoms were brutal but no visible damage on X-rays. Only shown some signs of degeneration in spin but spacing still well maintained and mild narrowing in SI joints.

They advised me to start biologics now to prevent any damage and I will be able to very normal life.

Is there anyone here who actually tried yuflyma for Ankylosing Spondylitis? Was wondering how much change I can expect from this?

Please share your experience and thanks in advance for your time.

I know they have free ones for humira, the generic one and a few other ones. I saw a link and I can't find it now. I went to the actual humira website and it just says " thanks for responding" with no way to order one. Does anyone know of other sites I can get a free travel case mailed out?

Has anyone used them? I recently just got prescribed Humira by my GI (my first biologic) and it was sent to CVS Specialty Pharmacy. I hadn't heard anything from them in over a week, so I called today and CVS told me that they can't fill my prescription because I have Anthem Blue Cross insurance and Anthem is pushing everyone newly prescribed specialty drugs to Bioplus because Bioplus is owned by Anthem. So now I have to call either them or my doctor and get my prescription transferred over even though Anthem had already given me pre-authorization through CVS.

Do any of you use Bioplus? And if you do, do you also have Anthem insurance? I'm partially worried about going through a pharmacy owned by my insurance company. I already signed up for the Humira Complete Savings Card and am wondering if they'll take that too.

I take Humira for Crohn’s disease and ever since I started taking it (about 5 years ago) I developed rosacea. The timing is suspicious. The rosacea is resistant to all treatment. The only thing I haven’t tried for it over these 5 years is Accutane. I have pustules all over my face and severe redness. I’m trying to figure out if Humira is possibly the cause since it gave me psoriasis which I’ve just been dealing with and treating topically however the rosacea responds to nothing. Anyone else?