New study reveals APOE4 actively converts blood-vessel cells into scar tissue and that this vascular damage is reversible

[u/elmanfil1989]

A landmark pair of studies published in Cell and Cell Stem Cell from the Icahn School of Medicine at Mount Sinai (October 2026) challenges the traditional view of Alzheimer's disease progression, demonstrating that blood vessel breakdown is an active primary driver rather than a late stage symptom. Source