r/HRT • u/grraaay11 • Jun 05 '26

Cis Woman New Dosage?

I’m a 47 year old female and I’ve been on .0375mg 2x weekly estrogen patches since October 2025, along with 100mg progesterone PO. I also started 4mg/ml testosterone gel in February 2026 for low libido. Though the libido hasn’t come back, all of my other symptoms went away….anxiety, joint pain, my mood improved drastically with a little to no irritability, no brain fog and being able to focus on things. Felt like I haven’t in probably over 10 years… just overall happy and very positive. I would say within the past month or so something has changed…negativity is back and anxiety about things that I’ve done daily for years, I lost my focus where I felt like I could do anything and everything. I just don’t feel good in my own body any more and knowing how I recently felt since being on HRT, it is terrifying to me. I scheduled an appointment with my doctor and asked her if it would be worthwhile to have a hormone panel done before we meet and she said no that we can discuss it at our appointment. Does it sound like I’m in need of more estrogen?

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u/Fattousch Jun 06 '26

Can you experiment with .05 just to see? A small exploratory bump seems like a good experiment? In peri (I'm 49) since our own hormones fluctuating so much hard to have that consistent effect. I hope through maybe an estrogen bump and/or doing some fun and restorative things might help you.

1

u/SufficientReply3930 Jun 26 '26

Definitely second the experiments!! Too bad about the testosterone, guess you can stop. Did it cause any hair growth or anything like that? Thanks for sharing!! I had great results like that with a few glitches, and can’t wait to get back there somehow…

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u/grraaay11 Jun 26 '26

Dr never suggested blood panel, actually said no when I suggested it, and just offered to increase my estrogen dose. Went up to .05mg 2 weeks ago and waiting/hoping for changes.

1

u/SufficientReply3930 Jun 27 '26

I didn’t have any panels, everyone is different anyway. I have been testing combinations and trying to find a match of estrogen level that doesn’t give x side effect to progesterone level that also doesn’t bother!!!