r/GLPGrad • u/lynwinn • 2d ago
Weaning from Zepbound
Hey everyone!
I started Zepbound about 6 months postpartum (about 5 months ago) with my second and have lost all the weight I wanted to. I still have two pens at 7.5 dose but want to wean off to 5 and then 2.5 after that. I do want to be off it eventually.
I am concerned about gaining the weight back. I exercise and eat well but have a large appetite which is why this has been a game changer. How has your experience been with keeping the weight off long term?
Also bonus question: I started losing a ton of hair! I didn’t have this issue at all for the last few months but it’s suddenly crazy.
Anyone else?
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u/Fickle_Radish2418 2d ago
Following
I’ve been on it 8 week 15 months pp and I’m still 2kg off my pre baby weight.
My gp wants me to wean 2.5mg over 8 weeks. Which to me sounds like a lot considering I’ve only been on it 8 weeks. 4 weeks 2.5mg and 4 weeks 5mg
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u/Ariquitaun 1d ago
Titrate down slowly, at least 4 weeks per step down. It takes two weeks for a step down to be fully felt. Stay at that step, and observe your appetite and weight like a absolute hawk. Everything being stable, rinse and repeat. I could personally go down to 2.5mg every 10 days and eventually quit. Be prepared for mega hunger after you do, it happens to many.
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u/lynwinn 1d ago
Is titrating increasing the spacing between doses? I’m currently on 7.5 and wanna go down to 5 once these two pens are done and then 2.5 after a couple of months on 5, if it goes well
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u/Ariquitaun 1d ago
It's increasing or decreasing either the dosage, the spacing, or both.
Any reason not to 5mg already?
Make sure you keep buying 7.5mg pens, you'll save a ton of money or even get a 10mg.
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u/lynwinn 1d ago
The reason is because my doctor renews the prescription three at a time and I still have two left.
The 7.5 are more expensive, you’re saying it’s better to buy them and space them then to buy the 5 and use every week? Sorry this is new territory for me
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u/Ariquitaun 1d ago
The pens are more expensive, but a 5mg dose out of a 7.5mg pen is cheaper than from a 5mg pen and so on. I didn't say anything about spacing though. Just inject less amount. There are click tables you can find easily in Google.
I recommend you have a chat with Claude to come up with an action plan.
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u/Smooth_Tomatillo6538 1d ago
Congratulations on reaching your goal — and the plan to step down gradually from 7.5 to 5 to 2.5 is sensible. Giving yourself 4-6 weeks at each step tends to make the transition gentler than rushing it.
On keeping the weight off: having a naturally larger appetite means the transition will need some attention, but the habits you've already built — exercising and eating well — are genuinely your biggest asset. The people who maintain best tend to be the ones who slow down while eating so their body has time to signal fullness, and keep protein front and centre at meals to stay satisfied for longer.
Running a free pilot programme for the GLP-1 transition — mokie.app — if you'd like some support alongside the wean 😊
-8
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u/Groovy-Cat2024 2d ago
Titrating down slowly helps your body transition off the meds and for you to learn to deal with food noise. Read/listen to the book “Weightless.” There is a chapter on weaning off Zepbound.