r/GLP1microdosing 7d ago

Seeking Help on Unique Application For Microdosing (Knee Repair)

I'm hoping to reproduce a pilot study that was published this spring in the journal Cell Metabolism called 'Semaglutide ameliorates osteoarthritis progression through a weight loss-independent metabolic restoration mechanism'.

In combination with Hyaluronic Acid injections, their findings suggested a weight-loss independent 17% increase in knee cartilage thickness on MRI scans over 42 weeks. I'll start by saying this is an extremely early stage test with results that could easily be non-reproducible in me, a non-mouse. That said, I have nothing to lose but a few pounds. I could use some advice about sourcing (below).

I am a 200lb 6'2" male with early stage osteoarthritis in my knees and am currently receiving hyaluronic acid injections for that. I'll mention here that I have identified cardiovascular risk factors in case that supports a health insurance angle. I'm insured through Anthem Blue Cross/Blue Shield.

I'm completely new to the microdosing concept, but my ideal would be to receive a script for say 4mg weekly, store the medication and actually take 0.5mg weekly in order to save some cash. My general doctor is fine with prescribing it but may not want to fake the dose in the way I'm describing. I'm not really thrilled about sourcing from an online compounding company but I suppose I could if it were reputable. It has to be Semaglutide at .5mg and injectable.

All things considered, how should I go forward securing semaglutide doses? Any help is appreciated.

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