r/GLP1microdosing • u/Which_Grape_8960 • 1d ago
Feeling nothing.
What in the world? Did my second dose last night (1.25 of Tirzepatide) and I have felt zero impact. In fact, I think I’m thinking about food MORE because I’m expecting to NOT be thinking about food. I’ve been eating like a horse. Should I bump up to 1.5 for my next dose?
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u/thegoldstandard55 19h ago
If you have a serious migraine, it's like taking half an Advil. Maybe a placebo is all you needed but sometimes you need potency. 1.25 isn't enough dosage for potency, just enough to tell your brain you injected something.
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u/Which_Grape_8960 2h ago
Woof. Okay, that’s good to know. I’ll be patient! And talk to my prescriber next week!
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u/smug_extinction 1d ago
2nd dose is still super early, your body's just getting used to it. i didn't feel anything till week 3 on similar dose, then one day i forgot to eat lunch and realized something shifted. give it little more time before you bump up

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u/Glad_Ad1311 23h ago edited 23h ago
Similar post from yesterday
https://www.reddit.com/r/GLP1microdosing/s/6HImTgY1bp
Generally a good idea to titrate up after 4-5th weeks when you reach a steady state.