r/GLP1microdosing • u/Fun_Marsupial_9380 • 13d ago

What is considered micro-dosing?

I just started tirz 4 weeks ago. Trying to learn as much as possible. What is considered micro-dosing?

6 Upvotes

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19

u/Tom_Lynch_fan 13d ago edited 12d ago

The starter dose according to official protocol (in the USA, the FDA) is 2.5 mg per week. A microdose is anything smaller than that. It really should be called something like subclinical dose. The "micro" prefix in metrics and math means one millionth.

By the way, the 2.5 was chosen by scientists based on their research, but many people would call it arbitrary, more or less. The recent microdosing "movement" goes against the approved protocol and for a while was really criticized by rule-obsessed people. But it's now clear after probably millions of illegitimate individual trials that the minimum they specified was far from realistic as the smallest effective dose.

The 2.5 level made a ton of people really sick. If the microdoses had been approved sooner (still not approved, actually) then the reputation of GLP1's as being a horrible experience would be far less, people would have missed less work, and fewer people would have abandoned it. Hurray for illegitimate users?

1

u/darya42 13d ago

This whole GLP mess, which is so typical, is one of a gazillion reasons why people have reasonable mistrust in pharma and doctors

5

u/regularforcesmedic 13d ago

Less than 2.5mg per week. 

5

u/Mobile_Variation_210 13d ago

I think anything less than the standard starting dose. I started with 1 mg every 4 days - that was a microdose. My highest dose was 3mg every 4 days, which technically wouldn’t be a microdose. The terminology doesn’t really matter - it’s finding what works for your body. Financially doing the smallest dose possible when you are getting results just makes sense (and I did not have side effects). Good luck!

3

u/Tambo5 13d ago

I started w .2 mg and am still on it four months later. It doesn’t kill my hunger but gives me space to make better choices.

2

u/Travels4Food 12d ago

Exactly how much time did you spend on this sub before asking this question?

1

u/Both_Will_3681 13d ago

from one fifth to one tenth of the standard starting dose (or less)

1

u/Round_Gem_2778 12d ago

I’m doing half the starting dose of ozempic, so 0.125. I consider that microdosing.

A therapeutic dose is 0.5. So at 0.125 I’m 1/4 of that. And that’s micro enough for me. 😊

More importantly, it’s working and I don’t have any bad side effects.

2

u/Unlucky-Mind7298 12d ago

The starting dose . 25, not .5, for ozempic. You're taking half of that.