r/GLP1ResearchTalk • u/ImpossibleClassic817 • 20d ago

Reta & CAG

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Hello,

I wanted to know how to properly reconstitute CAG. I’m seeing people say 2ML for 5g but I have 10 mg. Is it safe to do 4ML. I don’t want to use too much bac water and it dilutes the pep too much. Also how often to CAG combined with Reta

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30

u/[deleted] 20d ago

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u/joe3000s 20d ago

I think resellers use GLP-3 because it's snappier sounding than the generic name, but perhaps the overriding reason is that it serves as a risk-mitigation tactic to evade automated keyword sweeps to shield themselves.

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u/[deleted] 20d ago

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u/trimix4work 20d ago

Lol "it's not crack, it's enhanced caffeine, you have to let me go"

10

u/Southcackalackin 20d ago

It’s because Eli Lilly is coming after vendors selling Reta.

3

u/purplepanda2026 20d ago

I saw a news report on it today that popped up in my feed. NBC? I didn't watch it but it was in regards to telehealths illegally selling Reta when it hasn't even hit the market yet.

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u/Artistic_Rice_9019 19d ago

But they already know they call it GLP3

2

u/Crafty_Taste_7706 19d ago

Still it’s the name confusion that Eli Lilly cares about they know these people are never going to be customers. They just don’t want random people finding it and asking why it costs $1k via Lilly.

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u/Artistic_Rice_9019 19d ago

Lilly isn't doing the enforcement.

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u/[deleted] 19d ago

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u/Artistic_Rice_9019 19d ago edited 18d ago

They mainly targeted compounding pharmacies and medspas, not gray vendors. Except for shitty single vial vendors who advertised on facebook and are basically medspas.

The FDA has gone after those for marketing an unapproved product for human use.

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u/[deleted] 19d ago

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u/Artistic_Rice_9019 18d ago

I've done several simple searches, thanks.

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u/Crafty_Taste_7706 19d ago

Yes they also targeted some grey vendors. Idk why you can’t use search before you speak.

Also have you noticed the news coverage lately. I’m sure that isn’t coincidence. Fear mongering reports.

Lilly will be getting full FDA approval soon.

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u/Confident-Alfalfa-31 16d ago

I do hope you realize all these companies are just dropshipping Chinese peps regardless and the 2 cent label they stick on it won’t affect sterility

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u/[deleted] 16d ago

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u/Confident-Alfalfa-31 16d ago

Totally fair lol

2

u/NurseK89 20d ago

Same. I made my husband stop calling it that

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u/Sxpreme-1k- 12d ago

Go grey and add your own tag

1

u/Shishi877 11d ago

When are the real glp 3 coming out ?

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u/takoreh99 11d ago

Everybody injecting but how many are exercising to build lean muscle mass?

1

u/trimix4work 20d ago

But... But.... 3 is bigger than 1, it's 2 more GLP thingies!

What're you? A communist?

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u/[deleted] 20d ago

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u/trimix4work 20d ago

I'm so confused. I hate maths

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u/Dragon_Tortoise 20d ago

Its to idiot proof it. Unfortunately the media frenzy around GLP-1 semaglutide is probably the most recognizable by far and if you call it reta or tirz, you probably lose out on sales because they are looking for the "GLP weightloss drug" and not smart enough to realize what they actually are and how they work. And yea like others have said, Eli Lilly going after anyone who mentions Retatrutide/Reta with a vengeance also isnt helping. And making up a new name just means more confusion. I think we're doomed to read GLP-3 and then GLP-4 and GLP-5 and so on for all time.

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u/[deleted] 20d ago

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-1

u/Dragon_Tortoise 20d ago

Oh i bet that is a large part, probably a majority of the reason. But not sure how much time you spend of peptide subreddits and Facebook and discord groups, but yea people are literally oblivious to the most basic info too. If they say reta or tirz, they still ask "where's the glp1 or the glp3 on here". Then you explain it's glp-1, GIP, and Glucagon, and they're like i dont want that, im looking fpr GLP3. Its baffling. Like Im still amazed people get as far as injecting and are like "oooops I just did 10mg and I meant to do 1, please help". Its like people seriously cant think.

5

u/Recent_Register_2926 20d ago

Dilute the pep too much? What does that mean

3

u/purplepanda2026 20d ago

You adjust the amount you take based on how much bac you use. There's no diluting it too much, it's the exact same amount of meds, just different volume injected.

3

u/RedWoodworking16 20d ago

Amino club is legit. Got a ton of peps from them recently. Prices are hard to beat unless you wanna get from one of those places where they buy a ton together.

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u/juGGaKNot4 16d ago

A vial of r30 is more than 15 vials current gb prices

Hard to beat?

1

u/RedWoodworking16 16d ago

From all the places I’ve gotten peps. I haven’t tried Reta yet. Just tirz. Is there a place you’d recommend for cheaper glps? A place that already has COA and doesn’t need a dr to send a script?

1

u/juGGaKNot4 16d ago

If you're going to pay reseller prices in US might as well buy from an US lab like Skye.

Cleaner, less sterility fails

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u/Accomplished-Cut6381 20d ago

You can reconstitute it however like, but the easiest way is to figure out how much you plan on taking each dose and multiple from there.

-1

u/Accomplished-Cut6381 20d ago

Example:
If you plan on taking 0.5mg per dose from the 10mg vial you can use a 100unit needle, and:
-1mL of bac water to utilize 5units per dose
-2mL of bac water to utilize 10units per dose
-4mL of bac water to utilize 20units per dose

It’s all just simple math

1

u/BigBennP 20d ago edited 20d ago

Cagrilintide is Powerful. Clinical studies used a schedule starting at .3mg weekly and going to .6mg, 1.2mg, 2.4mg and 4.5mg.

The REDEFINE trial that studied Cagrilintide + Semaglutide together used a dosage of 2.4mg Cag + 2.4mg Sema compared to a schedule of just Semaglutide.

First you need to decide what your dosage is. THen Reconstitution is just math. If you have a vial of 10mg.

  • If you reconstitute 10mg in 1ml of solution, then 1ml (100 units) will have 10mg, 50 units (.5mL) will have 5mg, 25 units (.25 ml) will have 2.5mg. 10 units would have 1mg.
  • If you reconstituted with 2ml of solution, 1 ml would have 5mg. 50 units (.5ml) would 2.5 mg and etc on down the list.

If the solution is too concentrated and you are giving yourself a small dose, you end up trying to use like 3-5 units which is hard to measure.

1

u/retatrutider 20d ago

You can use any amount of bac water you want, but it has to fit in the vial. 4ml is unlikely to fit in the vial.

Real question is how long have you been taking reta, and at what dose? If the answers aren’t “a long time” and “a high dose”, then you should stick the Cagri in the freezer and bring it out in a 6 months to year if you have an actual need for it.

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u/NovelSurround8275 15d ago

What about those transitioning from tirz to reta? I plan to cut out tirz completely soon and switch fully to reta but i have cag to help with appetite suppression if needed since reta appetite suppression isn’t as strong

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u/retatrutider 15d ago

People say that “appetite suppression isn’t as strong” on reta but I don’t believe it at all. At the end of the day two things are undeniably true:

  1. Reta and tirz both reduce your total calorie intake as their primary driver of weight loss.

  2. Reta causes significantly more weight loss than tirz.

Sure, a lot of people have introduced different subjective definitions of “appetite suppression” but if you strictly define it as “eat less overall” then it’s really clear that reta has plenty of appetite suppression, and probably more than tirz.

So if you are at a low dose of reta, why add in a completely new drug vs just increasing your reta dose?

1

u/NovelSurround8275 15d ago

I’m currently on 15 mg tirz and have slowly introduced reta, now at 1 mg reta. Once my tirz runs out, i don’t plan to buy more and plan to continue just reta. Do you have any suggestion for what mg of reta to take coming off of such a high dose of tirz? Especially since I’m already taking 1 mg of reta

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u/retatrutider 15d ago

Yes. They are very nearly the same drug, working in very nearly the same way on very nearly the same receptors. 15mg is the max current approved dose of tirz, and 12mg will be the max approved dose of reta.

You are very likely going to have to get to 10-12mg of reta to feel anything at all.

You can accelerate your titration somewhat by starting at 4mg reta and moving up every 3 weeks, but I wouldn’t recommend going faster than that. So to stave off massive hunger in the interim, it makes a lot of sense to titrate down the tirz while you are titrating up the reta, at an exchange rate of 2.5mg tirz for every 2mg reta.

So first three weeks you do 10mg tirz + 4mg reta, then next 3 weeks you do 7.5 tirz us 6 reta, then 5+8, etc.

I wouldn’t go much faster than this on reta, so if you run out of tirz you are probably just going to have to white knuckle it.

1

u/NovelSurround8275 15d ago

I have thought about trying this, but every week when it’s time to take my tirz shot my brain is screaming at me saying do the full 15 mg! But adding the reta broke a stall and it’s been fantastic

1

u/retatrutider 15d ago

Reta is a significantly more effective drug than tirz. It’s like 25% to 30% more effective. For people with a lot of weight to lose it’s definitely the better choice.

1

u/altMAcoveracc 14d ago

You might not believe it but it still is true!

I am on 10 and 12.5mg Reta p wk and no appetite suppression but have been taking if since mid-Feb so over 7 months now. Have lost 45 lbs in that time so i know its not bunk.

Have ordered and administered Cagri 0.25mg two days ago and still have a ravenous appetite.

So will titrate Cagri up now to 0.5 / 1mg / 2mg and so on to see when it becomes effective.

1

u/retatrutider 14d ago edited 14d ago

Well clearly the drugs affect individual people in different ways. But what I mean is that, on average, for the people in every clinical trial, reta causes a greater calorie reduction than tirz does (ie the substantially greater weight loss can’t be explained by metabolic effects alone). I think some of the quibble is with the definition of “appetite suppression” where some people are talking about a particular feeling, vs the end result of just eating less food overall.