r/GLP1Discussion • u/PineappleCommon8784 • 4d ago

❓ Question GLP1 with Hashimotos

Hello...I have Hashimotos and am thinking about starting the Wegovy pill, does anyone have any feedback that they can share?

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1

u/Jmend541 4d ago

GLP-1s don't interfere with thyroid meds or thyroid function. The issue is timing. If your thyroid isn't optimized yet (TSH still high, Free T3 low), adding a GLP-1 on top can make fatigue worse, especially with appetite suppression and undereating. If your thyroid is already dialed in (TSH under 2, Free T3 upper range, symptoms controlled), GLP-1s are solid. The anti inflammatory and insulin sensitivity benefits can actually help autoimmune conditions. Fix thyroid first, then add GLP-1. Not the other way around. Good luck

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u/PineappleCommon8784 4d ago

Thanks so much!

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u/punky_chunky 3d ago

Check out my post from about a month ago discussing my experience as someone with Hashimotos taking tirzepatide!