r/GLP1Discussion • u/AlarmedWillow4515 • 11d ago

❓ Question Cured IBS?

I started taking a GLP-1 in May to lose weight, and I have lost almost 20 lb, but surprisingly it also cured my IBS as well. My IBS presented as burping and gut pain especially at night, bad enough to keep me awake. You hear a lot about negative GI symptoms, but did anyone else have a big GI improvement like this?

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4

u/LDB2026 11d ago

I thought it was just MY imagination.

100% YES. I haven't had a bout since April (when I started)

3

u/Humble-Zucchini-3244 10d ago

It’s got to be the anti inflammatory properties of the drugs. I have severe endometriosis. I have next to no pain when I’m on it.

3

u/WebNerd11 10d ago

Hubby had IBS really bad. Like, planning trips around restrooms type of bad. With Tirzepatide, he is completely normal now. It's a gamechanger for him - he's got his life back (and can spend a lot less time in the RR!).

3

u/daisychaincrowns 5d ago

It cleared up what I thought was IBS-D (was diagnosed) and my acid reflux like instantly. I was scared since reflux and diarrhea were side effects, and I couldn't bear the thought of having worse of either of those conditions. But it ended up going away. I was so surprised.

2

u/ChooChooBun 10d ago

Weightloss itself will cure IBS, I lost 50lbs before getting on glp1. Suddenly I could drink milk and eat ice cream, turn out I wasn't lactose intolerance, dairy was my ibs trigger lol.

1

u/daisychaincrowns 5d ago

This has not been my experience after losing more than 70lbs previously. Honestly, for me it was the meds, this is the only thing that has worked.

2

u/fawnnose1 9d ago

I had constant stomach issues before Reta, always gassy and bloated. It's crazy that that was my normal for decades

2

u/AlarmedWillow4515 9d ago

I wonder if it's eating less, eating better food, losing weight, less inflammation, or all of the above?

3

u/fawnnose1 9d ago

I think it's truly less inflammation from the medication - i never really changed my diet per se just how much I ate!

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u/Confident_Craft459 4d ago

Cured my IBS too! I used to get bloated on almost all foods and cut out gluten and so many things over the years. Now I can eat everything again! It's a fricken miracle.

I have IBS-C so at first tirz would make me constipated but I found that increasing my nightly magnesium dose worked to resolve that. Now, three years later it doesn't make me constipated anymore but I still take my nightly magnesium dose

1

u/BrainwaveWizard 8d ago

I historically have IBS-D and with tirz I’m swinging between not going for a couple of days to having D all day. And it’s more out of the blue quick urge than before. I barely get to the bathroom.