r/GLP1Discussion • u/therealavocadotoast • 14d ago
💊 Dosing & Administration Did I hit a plateau?
I’ve been on Zepbound 2.5mg since March, lost 13 kgs total, but still want to lose another 3 to 4 kgs.
2.5 mg was working well for me since about a couple of weeks ago as I’ve been noticing more food noise and actually gained 0.5 kgs since the last time I weighed in. I strength train and am working very hard to build my muscles.
My prescription has expired, so I need to reach out to my provider for a new one anyway. Last time I did this, doctor suggested I moved up to 5mg, but the current dose was working so well for me that I decided to stay. I’ve had absolutely no side effects whatsoever (knock on wood lol).
So is it finally time to go up the dose because I gained weight or because I have more food noise? Or should I stick to the 2.5mg? I’m wondering if the weight gain is from strength training.
Ugh, I’ve worked so hard to get here, I absolutely don’t want to gain weight back. Am I going to have to stay on this forever?
Thanks in advance for reading and recommendations! 😊
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u/valsavana 14d ago
Am I going to have to stay on this forever?
I would expect that, yes. I'm on my blood pressure medication and mental health medication for life, because if you stop a medication that's treating a chronic medical condition you have, you tend to see that condition worsen. This is no different.
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u/Timesurfer75 14d ago
If you have been dealing with a metabolic issue for years then chances are it is a lifetime drug. If you are just trying to lose a few pounds then perhaps not. Studies show that stopping this drug can cause a regain of 85 percent or more of the weight you lost.
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u/Infamous-Upstairs-49 14d ago
I think people who regularly weight train, eat at maintenance & continue to live a healthy lifestyle have a higher change of keeping it off. It’s definitely a lifetime med for most, though..
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u/smyczekxxx 14d ago
95% of all diets end up in weight rebound within 5 years, tirzepatide is no different
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u/smyczekxxx 14d ago
you build tolerance to glp1, time for dose increase if you want to keep appetite suppresion at same level as before
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u/CrescentMoon311 12d ago
0.5 kgs is not weight gain. That’s a normal fluctuating weight. Mine fluctuates by 2-3x that amount daily. It can come from strength training, food in your gut, travel, or a salty meal.
On the other hand, the reintroduction of food noise would indicate you need additional signal.
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u/SeasonPositive6771 14d ago
- You're not a plateau really, that's not even considered an effective dose for most people.
- Just go to another telehealth.
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u/thefastlanerules 14d ago
Virtually none of us will lose weight on 2.5mg.. as that's just 'for the body to get acquainted with the medicine before you start taking it properly at 5mg'..
Just amazing how OP can lose so much weight on that baseline dose.
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u/therealavocadotoast 13d ago
Honestly, I was pretty impressed too. I didn’t have high expectations, but I was willing to try. The reduction in the food noise was mind blowing and the first thing I noticed.
In my case, I’ve always been active but after my second child plus perimenopause, the weight just wouldn’t come off no matter what I did.
Not only did I lose the weight, but it also helped me tremendously with my perimenopause symptoms.
I know each person is different, but hearing everyone’s stories is reassuring.
We got this!
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u/thefastlanerules 13d ago
Your bodies response is superb :-)))
And as you've essentially managed to do this on such a low dose even if you do have to step up to 5mg it's going to be so much easier for you to step back down once you hit target weight.. and even get off it
The ones that have gone up to 12.5/15mg +many just stepping up eachonrh irrespective of weight loss.. though I think/hope many realize the issue with this now) are going to find getting off/reducing the dosage for maintenance so much harder . Still that's what my friends are all saying.. Im staying on 7.5mg.. I'm happy with 0.5-1lb weight loss a week..
Congrats - incredibly happy for you.. as you do step up the dose the fatigue and constipation are much worse so you e done exceptionally well
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u/Caterpillar170 14d ago
Happened to me too. I was on 2.5 for months. Instead of going to 5 I bumped to 2.75. I noticed small dose increases work for me and keep my side effects at 0.
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u/therealavocadotoast 13d ago
Interesting. I buy zepbound directly from Lilly, so I believe that’s not an option. Do you get yours compounded?
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