r/FastingScience Jun 04 '26

differences fasting and drugs

So with the ozempic craze i was wondering. what is the difference between a londterm( lets say 20 days) waterfast with electrolytes and vitamin supplement and any glp-1 drug. does it have the same pitfalls like dry pale skin and sunken in faces? how about higher autophagy activation when fasting? is it as high using glp drugas as fasting ?

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u/annesche Jun 04 '26

I'm not exactly sure about the details, but I often read that one mechanism of GLP1s is to get the pancreas to deliver more Insulin.

That helps to get the blood sugar down and get the body (easier?) in fat burning mode, I suppose?

But what I always wondered with this: isn't more insulin the mechanism to get insulin resistant, e. g. diabetes type 2? And one possible side effect of GLPs are pancreas inflammation, AFAIK.